LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | CP466722 | 10 | uM | LJP5 | 72 | hr | 1401 | 2026 | 4245 | 0.4771 | 0.2567 |
| SK-BR-3 | CP724714 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 3625 | 4245 | 0.8590 | 0.8209 |
| SK-BR-3 | CP724714 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 2814 | 4245 | 0.6638 | 0.5469 |
| SK-BR-3 | CP724714 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 2441 | 4245 | 0.5768 | 0.4166 |
| SK-BR-3 | CP724714 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 2141 | 4245 | 0.5061 | 0.3052 |
| SK-BR-3 | CP724714 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1856 | 4245 | 0.4371 | 0.1900 |
| SK-BR-3 | CP724714 | 10 | uM | LJP5 | 72 | hr | 1401 | 1398 | 4245 | 0.3282 | -0.0075 |
| SK-BR-3 | Alvocidib | 0.04 | uM | LJP6 | 72 | hr | 1401 | 1580 | 4168 | 0.3793 | 0.0795 |
| SK-BR-3 | Alvocidib | 0.12 | uM | LJP6 | 72 | hr | 1401 | 964 | 4168 | 0.2315 | -0.2115 |
| SK-BR-3 | Alvocidib | 0.37 | uM | LJP6 | 72 | hr | 1401 | 959 | 4168 | 0.2302 | -0.2145 |
| SK-BR-3 | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 1401 | 948 | 4168 | 0.2274 | -0.2212 |
| SK-BR-3 | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 1401 | 903 | 4168 | 0.2170 | -0.2442 |
| SK-BR-3 | Alvocidib | 10 | uM | LJP6 | 72 | hr | 1401 | 970 | 4168 | 0.2330 | -0.2090 |
| SK-BR-3 | GW843682X | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3654 | 4168 | 0.8765 | 0.8390 |
| SK-BR-3 | GW843682X | 0.12 | uM | LJP6 | 72 | hr | 1401 | 2267 | 4168 | 0.5435 | 0.3565 |
| SK-BR-3 | GW843682X | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1457 | 4168 | 0.3490 | 0.0225 |
| SK-BR-3 | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1305 | 4168 | 0.3133 | -0.0441 |
| SK-BR-3 | GW843682X | 3.33 | uM | LJP6 | 72 | hr | 1401 | 1237 | 4168 | 0.2965 | -0.0775 |
| SK-BR-3 | GW843682X | 10 | uM | LJP6 | 72 | hr | 1401 | 1734 | 4168 | 0.4157 | 0.1431 |
| SK-BR-3 | HG-5-113-01 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 3952 | 4245 | 0.9310 | 0.9123 |
| SK-BR-3 | HG-5-113-01 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4041 | 4245 | 0.9553 | 0.9457 |
| SK-BR-3 | HG-5-113-01 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 3418 | 4245 | 0.8048 | 0.7437 |
| SK-BR-3 | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1494 | 4245 | 0.3516 | 0.0379 |
| SK-BR-3 | HG-5-113-01 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1313 | 4245 | 0.3093 | -0.0421 |
| SK-BR-3 | HG-5-113-01 | 10 | uM | LJP5 | 72 | hr | 1401 | 1269 | 4245 | 0.2991 | -0.0621 |