LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 AZD7762
0.04
uM
LJP6
 72
hr
 1209 1961 4012 0.4890 0.3221
MCF7 Dasatinib
0.04
uM
LJP6
 72
hr
 1209 1642 4012 0.4094 0.1929
MCF7 Crizotinib
0.04
uM
LJP5
 72
hr
 1209 3621 4203 0.8617 0.8409
MCF7 HG-5-113-01
0.04
uM
LJP5
 72
hr
 1209 3957 4203 0.9412 0.9334
MCF7 AT-7519
0.04
uM
LJP6
 72
hr
 1209 1716 4012 0.4263 0.2189
MCF7 BMS345541
0.04
uM
LJP6
 72
hr
 1209 4237 4012 1.0560 1.0640
MCF7 NVP-TAE684
0.04
uM
LJP6
 72
hr
 1209 1984 4012 0.4944 0.3304
MCF7 KIN001-043
0.04
uM
LJP6
 72
hr
 1209 3628 4012 0.9066 0.8906
MCF7 Lapatinib
0.04
uM
LJP6
 72
hr
 1209 3516 4012 0.8766 0.8534
MCF7 HG-5-88-01
0.04
uM
LJP6
 72
hr
 1209 3074 4012 0.7659 0.7136
MCF7 CP466722
0.04
uM
LJP5
 72
hr
 1209 4412 4203 1.0522 1.0586
MCF7 YM 201636
0.04
uM
LJP5
 72
hr
 1209 4290 4203 1.0216 1.0245
MCF7 Seliciclib
0.04
uM
LJP5
 72
hr
 1209 4445 4203 1.0582 1.0640
MCF7 AZD8055
0.04
uM
LJP6
 72
hr
 1209 1199 4012 0.2986 -0.0063
MCF7 JW-7-24-1
0.04
uM
LJP6
 72
hr
 1209 2904 4012 0.7236 0.6583
MCF7 HG-6-64-01
0.04
uM
LJP6
 72
hr
 1209 4320 4012 1.0763 1.0866
MCF7 Sigma A6730
0.04
uM
LJP5
 72
hr
 1209 3392 4203 0.8075 0.7755
MCF7 Saracatinib
0.04
uM
LJP6
 72
hr
 1209 3381 4012 0.8425 0.8111
MCF7 Dasatinib
0.04
uM
LJP5
 72
hr
 1209 3206 4203 0.7621 0.7182
MCF7 Selumetinib
0.04
uM
LJP6
 72
hr
 1209 3122 4012 0.7787 0.7308
MCF7 CGP60474
0.04
uM
LJP5
 72
hr
 1209 3388 4203 0.8081 0.7768
MCF7 Neratinib
0.04
uM
LJP5
 72
hr
 1209 3690 4203 0.8761 0.8552
MCF7 CP724714
0.04
uM
LJP5
 72
hr
 1209 3813 4203 0.9088 0.8972
MCF7 SU11274
0.04
uM
LJP5
 72
hr
 1209 4485 4203 1.0671 1.0727
MCF7 Celastrol
0.04
uM
LJP6
 72
hr
 1209 4182 4012 1.0446 1.0523