LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Palbociclib
0.04
uM
LJP6
 72
hr
 1209 2761 4012 0.6898 0.6137
MCF7 Erlotinib
0.04
uM
LJP5
 72
hr
 1209 3874 4203 0.9233 0.9139
MCF7 BX-912
0.04
uM
LJP5
 72
hr
 1209 3738 4203 0.8904 0.8752
MCF7 CGP60474
0.04
uM
LJP5
 72
hr
 1209 3388 4203 0.8081 0.7768
SK-BR-3 PIK-93
0.04
uM
LJP5
 72
hr
 1401 4442 4245 1.0468 1.0584
MCF7 CGP60474
0.04
uM
LJP6
 72
hr
 1209 681 4012 0.1703 -0.2823
MCF7 Dovitinib
0.04
uM
LJP5
 72
hr
 1209 4004 4203 0.9540 0.9491
SK-BR-3 Mitoxantrone
0.04
uM
LJP5
 72
hr
 1401 1595 4245 0.3753 0.0810
MCF7 Selumetinib
0.04
uM
LJP6
 72
hr
 1209 3122 4012 0.7787 0.7308
SK-BR-3 AT-7519
0.04
uM
LJP6
 72
hr
 1401 2511 4168 0.6031 0.4499
SK-BR-3 Radicicol
0.04
uM
LJP6
 72
hr
 1401 2168 4168 0.5199 0.3189
SK-BR-3 AZD7762
0.04
uM
LJP6
 72
hr
 1401 1907 4168 0.4574 0.2158
SK-BR-3 Withaferin A
0.04
uM
LJP6
 72
hr
 1401 4473 4168 1.0732 1.0919
SK-BR-3 Alvocidib
0.04
uM
LJP6
 72
hr
 1401 1580 4168 0.3793 0.0795
MCF7 MK2206
0.04
uM
LJP6
 72
hr
 1209 2425 4012 0.6048 0.4946
SK-BR-3 Sorafenib
0.04
uM
LJP6
 72
hr
 1401 3852 4168 0.9237 0.9010
MCF7 Afatinib
0.04
uM
LJP6
 72
hr
 1209 3665 4012 0.9147 0.9003
MCF7 HG-5-88-01
0.04
uM
LJP6
 72
hr
 1209 3074 4012 0.7659 0.7136
SK-BR-3 CP466722
0.04
uM
LJP5
 72
hr
 1401 4863 4245 1.1519 1.1903
MCF7 GSK 690693
0.04
uM
LJP5
 72
hr
 1209 2794 4203 0.6647 0.5926
MCF7 AZD-6482
0.04
uM
LJP5
 72
hr
 1209 4152 4203 0.9873 0.9851
MCF7 CP466722
0.04
uM
LJP5
 72
hr
 1209 4412 4203 1.0522 1.0586
MCF7 Gefitinib
0.04
uM
LJP6
 72
hr
 1209 4112 4012 1.0253 1.0295
MDA-MB-231 CGP60474
0.04
uM
LJP5
 72
hr
 1235 3304 4660 0.7086 0.6698
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 72
hr
 1235 3892 4405 0.8837 0.8696