LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A CGP60474
0.04
uM
LJP6
 72
hr
 962 400 10692 0.0375 -0.2234
MCF 10A AZD7762
10
uM
LJP6
 72
hr
 962 414 10692 0.0388 -0.2181
Hs 578T Mitoxantrone
3.33
uM
LJP5
 72
hr
 658 154 3933 0.0392 -0.4301
MCF 10A PF431396
10
uM
LJP5
 72
hr
 962 413 10512 0.0392 -0.2201
Hs 578T Mitoxantrone
3.33
uM
LJP6
 72
hr
 658 147 3761 0.0393 -0.4481
MDA-MB-231 Mitoxantrone
3.33
uM
LJP5
 72
hr
 1235 185 4660 0.0399 -0.6288
BT-20 Mitoxantrone
10
uM
LJP5
 72
hr
 1097 158 3846 0.0411 -0.6586
MCF7 HG-6-64-01
10
uM
LJP6
 72
hr
 1209 170 4012 0.0422 -0.6806
MCF 10A SNS-032
0.37
uM
LJP6
 72
hr
 962 452 10692 0.0423 -0.1955
MCF 10A Mitoxantrone
3.33
uM
LJP6
 72
hr
 962 460 10692 0.0431 -0.1920
MCF 10A JNK-9L
3.33
uM
LJP6
 72
hr
 962 460 10692 0.0431 -0.1928
MCF 10A GSK1059615
10
uM
LJP5
 72
hr
 962 480 10512 0.0457 -0.1828
MCF 10A GSK1059615
10
uM
LJP6
 72
hr
 962 491 10692 0.0460 -0.1764
Hs 578T LDN-193189
3.33
uM
LJP5
 72
hr
 658 183 3933 0.0465 -0.3919
MDA-MB-231 Mitoxantrone
3.33
uM
LJP6
 72
hr
 1235 205 4405 0.0467 -0.6246
Hs 578T WH-4-025
10
uM
LJP5
 72
hr
 658 186 3933 0.0473 -0.3913
MCF 10A Radicicol
10
uM
LJP5
 72
hr
 962 495 10512 0.0473 -0.1775
MCF 10A Dasatinib
10
uM
LJP6
 72
hr
 962 514 10692 0.0481 -0.1662
MCF 10A Mitoxantrone
10
uM
LJP5
 72
hr
 962 509 10512 0.0484 -0.1687
MCF 10A QL-XII-47
10
uM
LJP6
 72
hr
 962 522 10692 0.0488 -0.1619
Hs 578T HG-6-64-01
10
uM
LJP6
 72
hr
 658 184 3761 0.0492 -0.3976
MCF 10A WZ3105
0.37
uM
LJP5
 72
hr
 962 522 10512 0.0498 -0.1629
MCF 10A Mitoxantrone
10
uM
LJP6
 72
hr
 962 552 10692 0.0517 -0.1484
MDA-MB-231 HG-6-64-01
10
uM
LJP6
 72
hr
 1235 234 4405 0.0524 -0.6111
MCF 10A Withaferin A
10
uM
LJP6
 72
hr
 962 574 10692 0.0537 -0.1393