LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 SU11274
0.12
uM
LJP5
 72
hr
 1235 4521 4660 0.9691 0.9665
MDA-MB-231 SU11274
0.37
uM
LJP5
 72
hr
 1235 4429 4660 0.9495 0.9454
MDA-MB-231 SU11274
1.11
uM
LJP5
 72
hr
 1235 4176 4660 0.8960 0.8881
MDA-MB-231 SU11274
3.33
uM
LJP5
 72
hr
 1235 3672 4660 0.7873 0.7642
MDA-MB-231 SU11274
10
uM
LJP5
 72
hr
 1235 1156 4660 0.2478 -0.0357
MDA-MB-231 Canertinib
0.04
uM
LJP6
 72
hr
 1235 4465 4405 1.0137 1.0151
MDA-MB-231 Canertinib
0.12
uM
LJP6
 72
hr
 1235 4322 4405 0.9808 0.9787
MDA-MB-231 Canertinib
0.37
uM
LJP6
 72
hr
 1235 4023 4405 0.9129 0.9026
MDA-MB-231 Canertinib
1.11
uM
LJP6
 72
hr
 1235 3446 4405 0.7819 0.7482
MDA-MB-231 Canertinib
3.33
uM
LJP6
 72
hr
 1235 2468 4405 0.5613 0.4593
MDA-MB-231 Canertinib
10
uM
LJP6
 72
hr
 1235 635 4405 0.1440 -0.3059
MDA-MB-231 NVP-AEW541
0.04
uM
LJP5
 72
hr
 1235 4811 4660 1.0342 1.0363
MDA-MB-231 NVP-AEW541
0.12
uM
LJP5
 72
hr
 1235 4801 4660 1.0313 1.0332
MDA-MB-231 NVP-AEW541
0.37
uM
LJP5
 72
hr
 1235 4603 4660 0.9899 0.9904
MDA-MB-231 NVP-AEW541
1.11
uM
LJP5
 72
hr
 1235 4625 4660 0.9930 0.9927
MDA-MB-231 NVP-AEW541
3.33
uM
LJP5
 72
hr
 1235 4489 4660 0.9634 0.9614
MDA-MB-231 NVP-AEW541
10
uM
LJP5
 72
hr
 1235 1349 4660 0.2868 0.0328
MDA-MB-231 PHA-665752
0.04
uM
LJP5
 72
hr
 1235 4901 4660 1.0529 1.0554
MDA-MB-231 PHA-665752
0.12
uM
LJP5
 72
hr
 1235 4659 4660 1.0008 1.0015
MDA-MB-231 PHA-665752
0.37
uM
LJP5
 72
hr
 1235 4719 4660 1.0126 1.0131
MDA-MB-231 PHA-665752
1.11
uM
LJP5
 72
hr
 1235 4645 4660 0.9983 0.9991
MDA-MB-231 PHA-665752
3.33
uM
LJP5
 72
hr
 1235 4343 4660 0.9333 0.9299
MDA-MB-231 PHA-665752
10
uM
LJP5
 72
hr
 1235 131 4660 0.0282 -0.6902
MDA-MB-231 PI103
0.04
uM
LJP6
 72
hr
 1235 3222 4405 0.7319 0.6869
MDA-MB-231 PI103
0.12
uM
LJP6
 72
hr
 1235 2668 4405 0.6061 0.5220