LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Pictilisib
1.11
uM
LJP6
 72
hr
 1235 2976 4405 0.6753 0.6140
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 72
hr
 1235 2904 4405 0.6591 0.5928
MDA-MB-231 Pictilisib
10
uM
LJP6
 72
hr
 1235 1869 4405 0.4245 0.2528
MDA-MB-231 PD184352
0.04
uM
LJP5
 72
hr
 1235 4379 4660 0.9390 0.9346
MDA-MB-231 PD184352
0.12
uM
LJP5
 72
hr
 1235 4050 4660 0.8682 0.8568
MDA-MB-231 PD184352
0.37
uM
LJP5
 72
hr
 1235 3778 4660 0.8099 0.7905
MDA-MB-231 PD184352
1.11
uM
LJP5
 72
hr
 1235 3376 4660 0.7236 0.6880
MDA-MB-231 PD184352
3.33
uM
LJP5
 72
hr
 1235 2937 4660 0.6293 0.5681
MDA-MB-231 PD184352
10
uM
LJP5
 72
hr
 1235 1449 4660 0.3105 0.0845
MDA-MB-231 PLX-4720
0.04
uM
LJP5
 72
hr
 1235 4328 4660 0.9268 0.9198
MDA-MB-231 PLX-4720
0.12
uM
LJP5
 72
hr
 1235 4456 4660 0.9549 0.9512
MDA-MB-231 PLX-4720
0.37
uM
LJP5
 72
hr
 1235 4537 4660 0.9709 0.9663
MDA-MB-231 PLX-4720
1.11
uM
LJP5
 72
hr
 1235 4404 4660 0.9438 0.9394
MDA-MB-231 PLX-4720
3.33
uM
LJP5
 72
hr
 1235 4064 4660 0.8698 0.8567
MDA-MB-231 PLX-4720
10
uM
LJP5
 72
hr
 1235 3832 4660 0.8209 0.8015
MDA-MB-231 Lapatinib
0.04
uM
LJP6
 72
hr
 1235 3964 4405 0.8995 0.8872
MDA-MB-231 Lapatinib
0.12
uM
LJP6
 72
hr
 1235 4135 4405 0.9386 0.9319
MDA-MB-231 Lapatinib
0.37
uM
LJP6
 72
hr
 1235 4253 4405 0.9655 0.9621
MDA-MB-231 Lapatinib
1.11
uM
LJP6
 72
hr
 1235 4123 4405 0.9361 0.9293
MDA-MB-231 Lapatinib
3.33
uM
LJP6
 72
hr
 1235 4234 4405 0.9619 0.9585
MDA-MB-231 Lapatinib
10
uM
LJP6
 72
hr
 1235 2602 4405 0.5916 0.5020
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 72
hr
 1235 3461 4405 0.7860 0.7536
MDA-MB-231 Sirolimus
0.12
uM
LJP6
 72
hr
 1235 3485 4405 0.7920 0.7614
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 72
hr
 1235 3473 4405 0.7889 0.7574
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 72
hr
 1235 3535 4405 0.8036 0.7754