LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Dasatinib
10
uM
LJP6
 72
hr
 1311 677 4935 0.1373 -0.2930
MDA-MB-231 Tozasertib
0.04
uM
LJP5
 72
hr
 1311 1493 5079 0.2940 0.0678
MDA-MB-231 Tozasertib
0.12
uM
LJP5
 72
hr
 1311 1381 5079 0.2719 0.0264
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 72
hr
 1311 1469 5079 0.2892 0.0590
MDA-MB-231 Tozasertib
1.11
uM
LJP5
 72
hr
 1311 1440 5079 0.2836 0.0485
MDA-MB-231 Tozasertib
3.33
uM
LJP5
 72
hr
 1311 1514 5079 0.2981 0.0757
MDA-MB-231 Tozasertib
10
uM
LJP5
 72
hr
 1311 1419 5079 0.2793 0.0405
MDA-MB-231 Imatinib
0.04
uM
LJP6
 72
hr
 1311 4853 4935 0.9835 0.9820
MDA-MB-231 Imatinib
0.12
uM
LJP6
 72
hr
 1311 4843 4935 0.9816 0.9797
MDA-MB-231 Imatinib
0.37
uM
LJP6
 72
hr
 1311 4897 4935 0.9927 0.9919
MDA-MB-231 Imatinib
1.11
uM
LJP6
 72
hr
 1311 4834 4935 0.9798 0.9780
MDA-MB-231 Imatinib
3.33
uM
LJP6
 72
hr
 1311 5047 4935 1.0226 1.0228
MDA-MB-231 Imatinib
10
uM
LJP6
 72
hr
 1311 4460 4935 0.9041 0.8970
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 72
hr
 1311 4655 4935 0.9432 0.9396
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
 72
hr
 1311 4110 4935 0.8333 0.8177
MDA-MB-231 NVP-TAE684
0.37
uM
LJP6
 72
hr
 1311 3917 4935 0.7937 0.7723
MDA-MB-231 NVP-TAE684
1.11
uM
LJP6
 72
hr
 1311 2840 4935 0.5758 0.4978
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 72
hr
 1311 1462 4935 0.2964 0.0585
MDA-MB-231 NVP-TAE684
10
uM
LJP6
 72
hr
 1311 1051 4935 0.2132 -0.1099
MDA-MB-231 CGP60474
0.04
uM
LJP5
 72
hr
 1311 3853 5079 0.7584 0.7356
MDA-MB-231 CGP60474
0.04
uM
LJP6
 72
hr
 1311 927 4935 0.1880 -0.1659
MDA-MB-231 CGP60474
0.12
uM
LJP5
 72
hr
 1311 1271 5079 0.2504 -0.0157
MDA-MB-231 CGP60474
0.12
uM
LJP6
 72
hr
 1311 791 4935 0.1603 -0.2326
MDA-MB-231 CGP60474
0.37
uM
LJP5
 72
hr
 1311 830 5079 0.1635 -0.2088
MDA-MB-231 CGP60474
0.37
uM
LJP6
 72
hr
 1311 812 4935 0.1646 -0.2219