LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 XMD11-50
1.11
uM
LJP6
 72
hr
 1311 2613 4935 0.5297 0.4340
MDA-MB-231 XMD11-50
3.33
uM
LJP6
 72
hr
 1311 1905 4935 0.3859 0.2152
MDA-MB-231 XMD11-50
10
uM
LJP6
 72
hr
 1311 1367 4935 0.2771 0.0213
MDA-MB-231 XMD11-85h
0.04
uM
LJP6
 72
hr
 1311 3815 4935 0.7730 0.7478
MDA-MB-231 XMD11-85h
0.12
uM
LJP6
 72
hr
 1311 4668 4935 0.9455 0.9415
MDA-MB-231 XMD11-85h
0.37
uM
LJP6
 72
hr
 1311 4551 4935 0.9222 0.9171
MDA-MB-231 XMD11-85h
1.11
uM
LJP6
 72
hr
 1311 4500 4935 0.9115 0.9048
MDA-MB-231 XMD11-85h
3.33
uM
LJP6
 72
hr
 1311 4256 4935 0.8623 0.8507
MDA-MB-231 XMD11-85h
10
uM
LJP6
 72
hr
 1311 2457 4935 0.4980 0.3885
MDA-MB-231 XMD16-144
0.04
uM
LJP5
 72
hr
 1311 2681 5079 0.5281 0.4408
MDA-MB-231 XMD16-144
0.12
uM
LJP5
 72
hr
 1311 1577 5079 0.3105 0.0979
MDA-MB-231 XMD16-144
0.37
uM
LJP5
 72
hr
 1311 1665 5079 0.3279 0.1291
MDA-MB-231 XMD16-144
1.11
uM
LJP5
 72
hr
 1311 1633 5079 0.3218 0.1188
MDA-MB-231 XMD16-144
3.33
uM
LJP5
 72
hr
 1311 1531 5079 0.3016 0.0825
MDA-MB-231 XMD16-144
10
uM
LJP5
 72
hr
 1311 774 5079 0.1525 -0.2374
MDA-MB-231 Erlotinib
0.04
uM
LJP5
 72
hr
 1311 4853 5079 0.9555 0.9539
MDA-MB-231 Erlotinib
0.12
uM
LJP5
 72
hr
 1311 4941 5079 0.9727 0.9717
MDA-MB-231 Erlotinib
0.37
uM
LJP5
 72
hr
 1311 5018 5079 0.9880 0.9878
MDA-MB-231 Erlotinib
1.11
uM
LJP5
 72
hr
 1311 5014 5079 0.9870 0.9865
MDA-MB-231 Erlotinib
3.33
uM
LJP5
 72
hr
 1311 4951 5079 0.9745 0.9733
MDA-MB-231 Erlotinib
10
uM
LJP5
 72
hr
 1311 3708 5079 0.7302 0.7022
MDA-MB-231 Gefitinib
0.04
uM
LJP6
 72
hr
 1311 5117 4935 1.0370 1.0382
MDA-MB-231 Gefitinib
0.12
uM
LJP6
 72
hr
 1311 5020 4935 1.0173 1.0172
MDA-MB-231 Gefitinib
0.37
uM
LJP6
 72
hr
 1311 5011 4935 1.0156 1.0162
MDA-MB-231 Gefitinib
1.11
uM
LJP6
 72
hr
 1311 4958 4935 1.0047 1.0042