LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
SK-BR-3 CGP60474
0.04
uM
LJP5
 72
hr
 2543 5802 5752 1.0087 1.0148
MCF7 NU7441
0.04
uM
LJP5
 72
hr
 1389 6255 5905 1.0608 1.0573
MCF7 PD173074
0.04
uM
LJP6
 72
hr
 1389 6234 5445 1.1449 1.1423
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 72
hr
 1311 4261 4935 0.8639 0.8518
MCF7 Seliciclib
0.04
uM
LJP5
 72
hr
 1389 5996 5905 1.0155 1.0149
MCF7 QL-X-138
0.04
uM
LJP6
 72
hr
 1389 3387 5445 0.6226 0.5715
SK-BR-3 Crizotinib
0.04
uM
LJP5
 72
hr
 2543 4361 5752 0.7581 0.5793
MCF7 OSI-027
0.04
uM
LJP6
 72
hr
 1389 5485 5445 1.0072 1.0073
MCF7 PF431396
0.04
uM
LJP5
 72
hr
 1389 4828 5905 0.8175 0.8158
MCF7 XMD11-50
0.04
uM
LJP6
 72
hr
 1389 4718 5445 0.8595 0.8378
MCF7 Vemurafenib
0.04
uM
LJP5
 72
hr
 1389 5823 5905 0.9859 0.9864
MCF7 WZ-4-145
0.04
uM
LJP6
 72
hr
 1389 3933 5445 0.7218 0.6937
MCF7 TWS119
0.04
uM
LJP5
 72
hr
 1389 6227 5905 1.0550 1.0522
MCF7 WYE-125132
0.04
uM
LJP6
 72
hr
 1389 1958 5445 0.3614 0.1917
MCF7 Crizotinib
0.04
uM
LJP5
 72
hr
 1389 4267 5905 0.7211 0.7069
MCF7 PF477736
0.04
uM
LJP5
 72
hr
 1389 3686 5905 0.6243 0.5960
MCF7 HG-6-64-01
0.04
uM
LJP6
 72
hr
 1389 6450 5445 1.1889 1.1853
MCF7 Y39983
0.04
uM
LJP6
 72
hr
 1389 5536 5445 1.0136 1.0098
SK-BR-3 A443654
0.04
uM
LJP6
 72
hr
 2543 1613 5418 0.2978 -0.3416
MCF7 Barasertib
0.04
uM
LJP5
 72
hr
 1389 2234 5905 0.3783 0.2554
MCF7 Pelitinib
0.04
uM
LJP5
 72
hr
 1389 5916 5905 1.0028 1.0029
MCF7 AZD8330
0.04
uM
LJP5
 72
hr
 1389 2293 5905 0.3881 0.2706
MCF7 LDN-193189
0.04
uM
LJP5
 72
hr
 1389 6186 5905 1.0473 1.0446
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 72
hr
 1311 3128 4935 0.6340 0.5758
MDA-MB-231 OSI-027
0.04
uM
LJP6
 72
hr
 1311 5123 4935 1.0380 1.0392