LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Palbociclib
0.04
uM
LJP6
 72
hr
 1389 4400 5445 0.8075 0.7926
MCF7 Erlotinib
0.04
uM
LJP5
 72
hr
 1389 5185 5905 0.8788 0.8801
MCF7 BX-912
0.04
uM
LJP5
 72
hr
 1389 4745 5905 0.8033 0.8007
MCF7 CGP60474
0.04
uM
LJP5
 72
hr
 1389 5969 5905 1.0110 1.0106
SK-BR-3 PIK-93
0.04
uM
LJP5
 72
hr
 2543 6046 5752 1.0512 1.0866
MCF7 CGP60474
0.04
uM
LJP6
 72
hr
 1389 727 5445 0.1339 -0.2802
MCF7 Dovitinib
0.04
uM
LJP5
 72
hr
 1389 5070 5905 0.8580 0.8580
SK-BR-3 Mitoxantrone
0.04
uM
LJP5
 72
hr
 2543 2003 5752 0.3482 -0.1839
MCF7 Selumetinib
0.04
uM
LJP6
 72
hr
 1389 4868 5445 0.8954 0.8915
SK-BR-3 AT-7519
0.04
uM
LJP6
 72
hr
 2543 5140 5418 0.9491 0.9072
SK-BR-3 Radicicol
0.04
uM
LJP6
 72
hr
 2543 3341 5418 0.6157 0.2801
SK-BR-3 AZD7762
0.04
uM
LJP6
 72
hr
 2543 2030 5418 0.3747 -0.1872
SK-BR-3 Withaferin A
0.04
uM
LJP6
 72
hr
 2543 5809 5418 1.0736 1.1383
SK-BR-3 Alvocidib
0.04
uM
LJP6
 72
hr
 2543 2952 5418 0.5448 0.1453
MCF7 MK2206
0.04
uM
LJP6
 72
hr
 1389 4071 5445 0.7484 0.7262
SK-BR-3 Sorafenib
0.04
uM
LJP6
 72
hr
 2543 5284 5418 0.9764 0.9589
MCF7 Afatinib
0.04
uM
LJP6
 72
hr
 1389 4541 5445 0.8383 0.8287
MCF7 HG-5-88-01
0.04
uM
LJP6
 72
hr
 1389 3675 5445 0.6770 0.6408
SK-BR-3 CP466722
0.04
uM
LJP5
 72
hr
 2543 6180 5752 1.0744 1.1255
MCF7 GSK 690693
0.04
uM
LJP5
 72
hr
 1389 4087 5905 0.6919 0.6763
MCF7 AZD-6482
0.04
uM
LJP5
 72
hr
 1389 6084 5905 1.0297 1.0278
MCF7 CP466722
0.04
uM
LJP5
 72
hr
 1389 6297 5905 1.0662 1.0623
MCF7 Gefitinib
0.04
uM
LJP6
 72
hr
 1389 5921 5445 1.0878 1.0876
MDA-MB-231 CGP60474
0.04
uM
LJP5
 72
hr
 1311 3853 5079 0.7584 0.7356
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 72
hr
 1311 4655 4935 0.9432 0.9396