LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Celastrol | 0.37 | uM | LJP6 | 72 | hr | 1694 | 11629 | 11217 | 1.0368 | 1.0267 |
| MCF 10A | PD173074 | 0.04 | uM | LJP6 | 72 | hr | 1694 | 11608 | 11217 | 1.0349 | 1.0253 |
| MCF 10A | PI103 | 0.04 | uM | LJP6 | 72 | hr | 1694 | 11606 | 11217 | 1.0346 | 1.0249 |
| MCF 10A | PLX-4720 | 1.11 | uM | LJP5 | 72 | hr | 1694 | 11583 | 11103 | 1.0433 | 1.0314 |
| MCF 10A | Enzastaurin | 1.11 | uM | LJP5 | 72 | hr | 1694 | 11564 | 11103 | 1.0414 | 1.0300 |
| MCF 10A | MK2206 | 0.04 | uM | LJP6 | 72 | hr | 1694 | 11562 | 11217 | 1.0307 | 1.0223 |
| MCF 10A | CHIR-99021 | 0.04 | uM | LJP6 | 72 | hr | 1694 | 11560 | 11217 | 1.0305 | 1.0221 |
| MCF 10A | JW-7-24-1 | 0.37 | uM | LJP6 | 72 | hr | 1694 | 11550 | 11217 | 1.0298 | 1.0217 |
| MCF 10A | R406 | 0.04 | uM | LJP6 | 72 | hr | 1694 | 11540 | 11217 | 1.0289 | 1.0210 |
| MCF 10A | TWS119 | 0.37 | uM | LJP5 | 72 | hr | 1694 | 11511 | 11103 | 1.0368 | 1.0266 |
| MCF 10A | JW-7-24-1 | 3.33 | uM | LJP6 | 72 | hr | 1694 | 11504 | 11217 | 1.0258 | 1.0187 |
| MCF 10A | NU7441 | 0.04 | uM | LJP5 | 72 | hr | 1694 | 11501 | 11103 | 1.0359 | 1.0262 |
| MCF 10A | QL-X-138 | 0.37 | uM | LJP6 | 72 | hr | 1694 | 11489 | 11217 | 1.0240 | 1.0173 |
| MCF 10A | TWS119 | 0.04 | uM | LJP5 | 72 | hr | 1694 | 11487 | 11103 | 1.0346 | 1.0252 |
| MCF 10A | CP466722 | 0.04 | uM | LJP5 | 72 | hr | 1694 | 11482 | 11103 | 1.0342 | 1.0249 |
| MCF 10A | Imatinib | 3.33 | uM | LJP6 | 72 | hr | 1694 | 11454 | 11217 | 1.0210 | 1.0151 |
| MCF 10A | JNK-9L | 0.04 | uM | LJP6 | 72 | hr | 1694 | 11450 | 11217 | 1.0206 | 1.0147 |
| MCF 10A | Sorafenib | 0.37 | uM | LJP6 | 72 | hr | 1694 | 11440 | 11217 | 1.0200 | 1.0145 |
| MCF 10A | Saracatinib | 0.04 | uM | LJP6 | 72 | hr | 1694 | 11431 | 11217 | 1.0191 | 1.0139 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 1694 | 11428 | 11217 | 1.0188 | 1.0136 |
| MCF 10A | Linifanib | 0.37 | uM | LJP6 | 72 | hr | 1694 | 11418 | 11217 | 1.0180 | 1.0131 |
| MCF 10A | SU11274 | 0.04 | uM | LJP5 | 72 | hr | 1694 | 11406 | 11103 | 1.0273 | 1.0200 |
| MCF 10A | PI103 | 0.12 | uM | LJP6 | 72 | hr | 1694 | 11398 | 11217 | 1.0162 | 1.0118 |
| MCF 10A | YM 201636 | 0.04 | uM | LJP5 | 72 | hr | 1694 | 11383 | 11103 | 1.0252 | 1.0184 |
| MCF 10A | Foretinib | 0.12 | uM | LJP5 | 72 | hr | 1694 | 11382 | 11103 | 1.0252 | 1.0184 |