LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 TGX221
0.12
uM
LJP5
 72
hr
 1311 4386 5079 0.8633 0.8547
MDA-MB-231 TGX221
0.37
uM
LJP5
 72
hr
 1311 4516 5079 0.8889 0.8828
MDA-MB-231 TGX221
1.11
uM
LJP5
 72
hr
 1311 4311 5079 0.8488 0.8389
MDA-MB-231 TGX221
3.33
uM
LJP5
 72
hr
 1311 3466 5079 0.6825 0.6446
MDA-MB-231 TGX221
10
uM
LJP5
 72
hr
 1311 4596 5079 0.9049 0.9002
MDA-MB-231 GSK1059615
0.04
uM
LJP5
 72
hr
 1311 5134 5079 1.0107 1.0107
MDA-MB-231 GSK1059615
0.04
uM
LJP6
 72
hr
 1311 5133 4935 1.0403 1.0415
MDA-MB-231 GSK1059615
0.12
uM
LJP5
 72
hr
 1311 4965 5079 0.9772 0.9762
MDA-MB-231 GSK1059615
0.12
uM
LJP6
 72
hr
 1311 4874 4935 0.9877 0.9868
MDA-MB-231 GSK1059615
0.37
uM
LJP5
 72
hr
 1311 4830 5079 0.9511 0.9493
MDA-MB-231 GSK1059615
0.37
uM
LJP6
 72
hr
 1311 4887 4935 0.9902 0.9896
MDA-MB-231 GSK1059615
1.11
uM
LJP5
 72
hr
 1311 3604 5079 0.7095 0.6777
MDA-MB-231 GSK1059615
1.11
uM
LJP6
 72
hr
 1311 3998 4935 0.8104 0.7909
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 72
hr
 1311 1914 5079 0.3771 0.2126
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 72
hr
 1311 3119 4935 0.6322 0.5728
MDA-MB-231 GSK1059615
10
uM
LJP5
 72
hr
 1311 2194 5079 0.4316 0.2947
MDA-MB-231 GSK1059615
10
uM
LJP6
 72
hr
 1311 2064 4935 0.4185 0.2672
MDA-MB-231 Brivanib
0.04
uM
LJP5
 72
hr
 1311 5226 5079 1.0291 1.0294
MDA-MB-231 Brivanib
0.12
uM
LJP5
 72
hr
 1311 4947 5079 0.9743 0.9732
MDA-MB-231 Brivanib
0.37
uM
LJP5
 72
hr
 1311 4983 5079 0.9814 0.9805
MDA-MB-231 Brivanib
1.11
uM
LJP5
 72
hr
 1311 5043 5079 0.9930 0.9926
MDA-MB-231 Brivanib
3.33
uM
LJP5
 72
hr
 1311 5080 5079 1.0005 1.0000
MDA-MB-231 Brivanib
10
uM
LJP5
 72
hr
 1311 4025 5079 0.7927 0.7757
MDA-MB-231 CHIR-99021
0.04
uM
LJP6
 72
hr
 1311 4664 4935 0.9452 0.9418
MDA-MB-231 CHIR-99021
0.12
uM
LJP6
 72
hr
 1311 4267 4935 0.8646 0.8532