LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 AZD 5438
0.04
uM
LJP6
 72
hr
 1311 4293 4935 0.8700 0.8593
MDA-MB-231 AZD 5438
0.12
uM
LJP6
 72
hr
 1311 3406 4935 0.6902 0.6474
MDA-MB-231 AZD 5438
0.37
uM
LJP6
 72
hr
 1311 2254 4935 0.4568 0.3274
MDA-MB-231 AZD 5438
1.11
uM
LJP6
 72
hr
 1311 1274 4935 0.2581 -0.0157
MDA-MB-231 AZD 5438
3.33
uM
LJP6
 72
hr
 1311 771 4935 0.1562 -0.2429
MDA-MB-231 AZD 5438
10
uM
LJP6
 72
hr
 1311 652 4935 0.1322 -0.3061
MDA-MB-231 Pelitinib
0.04
uM
LJP5
 72
hr
 1311 5209 5079 1.0254 1.0257
MDA-MB-231 Pelitinib
0.12
uM
LJP5
 72
hr
 1311 5253 5079 1.0345 1.0350
MDA-MB-231 Pelitinib
0.37
uM
LJP5
 72
hr
 1311 4647 5079 0.9149 0.9109
MDA-MB-231 Pelitinib
1.11
uM
LJP5
 72
hr
 1311 4330 5079 0.8526 0.8430
MDA-MB-231 Pelitinib
3.33
uM
LJP5
 72
hr
 1311 2847 5079 0.5605 0.4862
MDA-MB-231 Pelitinib
10
uM
LJP5
 72
hr
 1311 1052 5079 0.2072 -0.1071
MDA-MB-231 Luminespib
0.04
uM
LJP5
 72
hr
 1311 1013 5079 0.1995 -0.1240
MDA-MB-231 Luminespib
0.12
uM
LJP5
 72
hr
 1311 993 5079 0.1956 -0.1327
MDA-MB-231 Luminespib
0.37
uM
LJP5
 72
hr
 1311 1023 5079 0.2015 -0.1194
MDA-MB-231 Luminespib
1.11
uM
LJP5
 72
hr
 1311 1019 5079 0.2007 -0.1212
MDA-MB-231 Luminespib
3.33
uM
LJP5
 72
hr
 1311 1051 5079 0.2069 -0.1073
MDA-MB-231 Luminespib
10
uM
LJP5
 72
hr
 1311 992 5079 0.1953 -0.1334
MDA-MB-231 AZD8330
0.04
uM
LJP5
 72
hr
 1311 1710 5079 0.3368 0.1452
MDA-MB-231 AZD8330
0.12
uM
LJP5
 72
hr
 1311 1566 5079 0.3084 0.0945
MDA-MB-231 AZD8330
0.37
uM
LJP5
 72
hr
 1311 1522 5079 0.2999 0.0788
MDA-MB-231 AZD8330
1.11
uM
LJP5
 72
hr
 1311 1514 5079 0.2982 0.0764
MDA-MB-231 AZD8330
3.33
uM
LJP5
 72
hr
 1311 1657 5079 0.3264 0.1272
MDA-MB-231 AZD8330
10
uM
LJP5
 72
hr
 1311 1587 5079 0.3126 0.1024
MDA-MB-231 TGX221
0.04
uM
LJP5
 72
hr
 1311 4250 5079 0.8367 0.8253