LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | PF562271 | 0.12 | uM | LJP6 | 72 | hr | 1311 | 4387 | 4935 | 0.8887 | 0.8790 |
| MDA-MB-231 | PF562271 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 3973 | 4935 | 0.8050 | 0.7849 |
| MDA-MB-231 | PF562271 | 1.11 | uM | LJP6 | 72 | hr | 1311 | 3483 | 4935 | 0.7057 | 0.6658 |
| MDA-MB-231 | PF562271 | 3.33 | uM | LJP6 | 72 | hr | 1311 | 1954 | 4935 | 0.3962 | 0.2321 |
| MDA-MB-231 | PF562271 | 10 | uM | LJP6 | 72 | hr | 1311 | 883 | 4935 | 0.1790 | -0.1870 |
| MDA-MB-231 | PHA-793887 | 0.04 | uM | LJP6 | 72 | hr | 1311 | 2323 | 4935 | 0.4708 | 0.3484 |
| MDA-MB-231 | PHA-793887 | 0.12 | uM | LJP6 | 72 | hr | 1311 | 2138 | 4935 | 0.4333 | 0.2913 |
| MDA-MB-231 | PHA-793887 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 1482 | 4935 | 0.3003 | 0.0655 |
| MDA-MB-231 | PHA-793887 | 1.11 | uM | LJP6 | 72 | hr | 1311 | 1265 | 4935 | 0.2564 | -0.0190 |
| MDA-MB-231 | PHA-793887 | 3.33 | uM | LJP6 | 72 | hr | 1311 | 1055 | 4935 | 0.2138 | -0.1078 |
| MDA-MB-231 | PHA-793887 | 10 | uM | LJP6 | 72 | hr | 1311 | 742 | 4935 | 0.1505 | -0.2574 |
| MDA-MB-231 | QL-X-138 | 0.04 | uM | LJP6 | 72 | hr | 1311 | 4357 | 4935 | 0.8827 | 0.8730 |
| MDA-MB-231 | QL-X-138 | 0.12 | uM | LJP6 | 72 | hr | 1311 | 4378 | 4935 | 0.8870 | 0.8781 |
| MDA-MB-231 | QL-X-138 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 4191 | 4935 | 0.8493 | 0.8363 |
| MDA-MB-231 | QL-X-138 | 1.11 | uM | LJP6 | 72 | hr | 1311 | 3975 | 4935 | 0.8058 | 0.7862 |
| MDA-MB-231 | QL-X-138 | 3.33 | uM | LJP6 | 72 | hr | 1311 | 3250 | 4935 | 0.6588 | 0.6075 |
| MDA-MB-231 | QL-X-138 | 10 | uM | LJP6 | 72 | hr | 1311 | 940 | 4935 | 0.1906 | -0.1600 |
| MDA-MB-231 | QL-XII-47 | 0.04 | uM | LJP6 | 72 | hr | 1311 | 3981 | 4935 | 0.8067 | 0.7873 |
| MDA-MB-231 | QL-XII-47 | 0.12 | uM | LJP6 | 72 | hr | 1311 | 3558 | 4935 | 0.7210 | 0.6854 |
| MDA-MB-231 | QL-XII-47 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 2885 | 4935 | 0.5847 | 0.5102 |
| MDA-MB-231 | QL-XII-47 | 1.11 | uM | LJP6 | 72 | hr | 1311 | 2028 | 4935 | 0.4111 | 0.2560 |
| MDA-MB-231 | QL-XII-47 | 3.33 | uM | LJP6 | 72 | hr | 1311 | 1421 | 4935 | 0.2879 | 0.0427 |
| MDA-MB-231 | QL-XII-47 | 10 | uM | LJP6 | 72 | hr | 1311 | 1087 | 4935 | 0.2203 | -0.0935 |
| MDA-MB-231 | Torin1 | 0.04 | uM | LJP6 | 72 | hr | 1311 | 2746 | 4935 | 0.5567 | 0.4721 |
| MDA-MB-231 | Torin1 | 0.12 | uM | LJP6 | 72 | hr | 1311 | 2243 | 4935 | 0.4548 | 0.3238 |