LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Barasertib
0.04
uM
LJP5
 72
hr
 1311 1941 5079 0.3823 0.2224
MDA-MB-231 Barasertib
0.12
uM
LJP5
 72
hr
 1311 1628 5079 0.3207 0.1165
MDA-MB-231 Barasertib
0.37
uM
LJP5
 72
hr
 1311 1670 5079 0.3290 0.1319
MDA-MB-231 Barasertib
1.11
uM
LJP5
 72
hr
 1311 1656 5079 0.3261 0.1267
MDA-MB-231 Barasertib
3.33
uM
LJP5
 72
hr
 1311 1607 5079 0.3164 0.1089
MDA-MB-231 Barasertib
10
uM
LJP5
 72
hr
 1311 1507 5079 0.2967 0.0735
MDA-MB-231 Vemurafenib
0.04
uM
LJP5
 72
hr
 1311 4847 5079 0.9542 0.9525
MDA-MB-231 Vemurafenib
0.12
uM
LJP5
 72
hr
 1311 4839 5079 0.9528 0.9511
MDA-MB-231 Vemurafenib
0.37
uM
LJP5
 72
hr
 1311 4824 5079 0.9493 0.9463
MDA-MB-231 Vemurafenib
1.11
uM
LJP5
 72
hr
 1311 4731 5079 0.9314 0.9283
MDA-MB-231 Vemurafenib
3.33
uM
LJP5
 72
hr
 1311 4060 5079 0.7992 0.7829
MDA-MB-231 Vemurafenib
10
uM
LJP5
 72
hr
 1311 2744 5079 0.5403 0.4591
MDA-MB-231 Enzastaurin
0.04
uM
LJP5
 72
hr
 1311 4962 5079 0.9771 0.9760
MDA-MB-231 Enzastaurin
0.12
uM
LJP5
 72
hr
 1311 4986 5079 0.9817 0.9809
MDA-MB-231 Enzastaurin
0.37
uM
LJP5
 72
hr
 1311 4838 5079 0.9521 0.9494
MDA-MB-231 Enzastaurin
1.11
uM
LJP5
 72
hr
 1311 4705 5079 0.9265 0.9230
MDA-MB-231 Enzastaurin
3.33
uM
LJP5
 72
hr
 1311 4917 5079 0.9678 0.9666
MDA-MB-231 Enzastaurin
10
uM
LJP5
 72
hr
 1311 5142 5079 1.0125 1.0128
MDA-MB-231 Palbociclib
0.04
uM
LJP6
 72
hr
 1311 3634 4935 0.7362 0.7031
MDA-MB-231 Palbociclib
0.12
uM
LJP6
 72
hr
 1311 3289 4935 0.6665 0.6175
MDA-MB-231 Palbociclib
0.37
uM
LJP6
 72
hr
 1311 2996 4935 0.6069 0.5393
MDA-MB-231 Palbociclib
1.11
uM
LJP6
 72
hr
 1311 2692 4935 0.5454 0.4563
MDA-MB-231 Palbociclib
3.33
uM
LJP6
 72
hr
 1311 2426 4935 0.4915 0.3792
MDA-MB-231 Palbociclib
10
uM
LJP6
 72
hr
 1311 2153 4935 0.4363 0.2959
MDA-MB-231 PF562271
0.04
uM
LJP6
 72
hr
 1311 4542 4935 0.9203 0.9150