LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 MK2206
10
uM
LJP6
 72
hr
 1311 3977 4935 0.8061 0.7856
MDA-MB-231 AZD-6482
0.04
uM
LJP5
 72
hr
 1311 4816 5079 0.9484 0.9465
MDA-MB-231 AZD-6482
0.12
uM
LJP5
 72
hr
 1311 4556 5079 0.8972 0.8918
MDA-MB-231 AZD-6482
0.37
uM
LJP5
 72
hr
 1311 4495 5079 0.8849 0.8786
MDA-MB-231 AZD-6482
1.11
uM
LJP5
 72
hr
 1311 4174 5079 0.8217 0.8085
MDA-MB-231 AZD-6482
3.33
uM
LJP5
 72
hr
 1311 3845 5079 0.7569 0.7338
MDA-MB-231 AZD-6482
10
uM
LJP5
 72
hr
 1311 3001 5079 0.5906 0.5263
MDA-MB-231 NU7441
0.04
uM
LJP5
 72
hr
 1311 4964 5079 0.9771 0.9758
MDA-MB-231 NU7441
0.12
uM
LJP5
 72
hr
 1311 4629 5079 0.9112 0.9065
MDA-MB-231 NU7441
0.37
uM
LJP5
 72
hr
 1311 4539 5079 0.8936 0.8876
MDA-MB-231 NU7441
1.11
uM
LJP5
 72
hr
 1311 4461 5079 0.8781 0.8708
MDA-MB-231 NU7441
3.33
uM
LJP5
 72
hr
 1311 3739 5079 0.7361 0.7089
MDA-MB-231 NU7441
10
uM
LJP5
 72
hr
 1311 2194 5079 0.4318 0.3001
MDA-MB-231 OSI-027
0.04
uM
LJP6
 72
hr
 1311 5123 4935 1.0380 1.0392
MDA-MB-231 OSI-027
0.12
uM
LJP6
 72
hr
 1311 4501 4935 0.9120 0.9052
MDA-MB-231 OSI-027
0.37
uM
LJP6
 72
hr
 1311 4085 4935 0.8277 0.8106
MDA-MB-231 OSI-027
1.11
uM
LJP6
 72
hr
 1311 3732 4935 0.7561 0.7273
MDA-MB-231 OSI-027
3.33
uM
LJP6
 72
hr
 1311 3146 4935 0.6374 0.5797
MDA-MB-231 OSI-027
10
uM
LJP6
 72
hr
 1311 2254 4935 0.4567 0.3263
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 72
hr
 1311 3128 4935 0.6340 0.5758
MDA-MB-231 WYE-125132
0.12
uM
LJP6
 72
hr
 1311 2463 4935 0.4992 0.3901
MDA-MB-231 WYE-125132
0.37
uM
LJP6
 72
hr
 1311 2150 4935 0.4358 0.2944
MDA-MB-231 WYE-125132
1.11
uM
LJP6
 72
hr
 1311 1996 4935 0.4047 0.2453
MDA-MB-231 WYE-125132
3.33
uM
LJP6
 72
hr
 1311 1859 4935 0.3768 0.2001
MDA-MB-231 WYE-125132
10
uM
LJP6
 72
hr
 1311 1436 4935 0.2910 0.0485