LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Alvocidib | 1.11 | uM | LJP6 | 72 | hr | 1311 | 748 | 4935 | 0.1517 | -0.2544 |
| MDA-MB-231 | Alvocidib | 3.33 | uM | LJP6 | 72 | hr | 1311 | 734 | 4935 | 0.1489 | -0.2625 |
| MDA-MB-231 | Alvocidib | 10 | uM | LJP6 | 72 | hr | 1311 | 680 | 4935 | 0.1379 | -0.2909 |
| MDA-MB-231 | GW843682X | 0.04 | uM | LJP6 | 72 | hr | 1311 | 4692 | 4935 | 0.9506 | 0.9462 |
| MDA-MB-231 | GW843682X | 0.12 | uM | LJP6 | 72 | hr | 1311 | 4279 | 4935 | 0.8669 | 0.8551 |
| MDA-MB-231 | GW843682X | 0.37 | uM | LJP6 | 72 | hr | 1311 | 3026 | 4935 | 0.6130 | 0.5474 |
| MDA-MB-231 | GW843682X | 1.11 | uM | LJP6 | 72 | hr | 1311 | 1702 | 4935 | 0.3447 | 0.1443 |
| MDA-MB-231 | GW843682X | 3.33 | uM | LJP6 | 72 | hr | 1311 | 1202 | 4935 | 0.2436 | -0.0450 |
| MDA-MB-231 | GW843682X | 10 | uM | LJP6 | 72 | hr | 1311 | 1137 | 4935 | 0.2305 | -0.0722 |
| MDA-MB-231 | HG-5-113-01 | 0.04 | uM | LJP5 | 72 | hr | 1311 | 4993 | 5079 | 0.9828 | 0.9817 |
| MDA-MB-231 | HG-5-113-01 | 0.12 | uM | LJP5 | 72 | hr | 1311 | 4523 | 5079 | 0.8902 | 0.8835 |
| MDA-MB-231 | HG-5-113-01 | 0.37 | uM | LJP5 | 72 | hr | 1311 | 4160 | 5079 | 0.8189 | 0.8052 |
| MDA-MB-231 | HG-5-113-01 | 1.11 | uM | LJP5 | 72 | hr | 1311 | 2940 | 5079 | 0.5789 | 0.5118 |
| MDA-MB-231 | HG-5-113-01 | 3.33 | uM | LJP5 | 72 | hr | 1311 | 1817 | 5079 | 0.3578 | 0.1816 |
| MDA-MB-231 | HG-5-113-01 | 10 | uM | LJP5 | 72 | hr | 1311 | 1318 | 5079 | 0.2593 | 0.0011 |
| MDA-MB-231 | HG-5-88-01 | 0.04 | uM | LJP6 | 72 | hr | 1311 | 4077 | 4935 | 0.8265 | 0.8101 |
| MDA-MB-231 | HG-5-88-01 | 0.12 | uM | LJP6 | 72 | hr | 1311 | 4430 | 4935 | 0.8978 | 0.8903 |
| MDA-MB-231 | HG-5-88-01 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 4245 | 4935 | 0.8603 | 0.8485 |
| MDA-MB-231 | HG-5-88-01 | 1.11 | uM | LJP6 | 72 | hr | 1311 | 4219 | 4935 | 0.8552 | 0.8427 |
| MDA-MB-231 | HG-5-88-01 | 3.33 | uM | LJP6 | 72 | hr | 1311 | 4300 | 4935 | 0.8715 | 0.8607 |
| MDA-MB-231 | HG-5-88-01 | 10 | uM | LJP6 | 72 | hr | 1311 | 2950 | 4935 | 0.5978 | 0.5264 |
| MDA-MB-231 | HG-6-64-01 | 0.04 | uM | LJP6 | 72 | hr | 1311 | 4569 | 4935 | 0.9260 | 0.9212 |
| MDA-MB-231 | HG-6-64-01 | 0.12 | uM | LJP6 | 72 | hr | 1311 | 4753 | 4935 | 0.9631 | 0.9609 |
| MDA-MB-231 | HG-6-64-01 | 0.37 | uM | LJP6 | 72 | hr | 1311 | 4134 | 4935 | 0.8377 | 0.8229 |
| MDA-MB-231 | HG-6-64-01 | 1.11 | uM | LJP6 | 72 | hr | 1311 | 2532 | 4935 | 0.5131 | 0.4106 |