LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 AZD7762
0.04
uM
LJP6
 72
hr
 1235 1904 4056 0.4696 0.2871
MCF7 Dasatinib
0.04
uM
LJP6
 72
hr
 1235 1127 4056 0.2781 -0.0520
MCF7 Crizotinib
0.04
uM
LJP5
 72
hr
 1235 3325 4267 0.7794 0.7387
MCF7 HG-5-113-01
0.04
uM
LJP5
 72
hr
 1235 3513 4267 0.8246 0.7956
MCF7 AT-7519
0.04
uM
LJP6
 72
hr
 1235 3560 4056 0.8771 0.8520
MCF7 BMS345541
0.04
uM
LJP6
 72
hr
 1235 4482 4056 1.1046 1.1188
MCF7 NVP-TAE684
0.04
uM
LJP6
 72
hr
 1235 2633 4056 0.6499 0.5548
MCF7 KIN001-043
0.04
uM
LJP6
 72
hr
 1235 3928 4056 0.9685 0.9632
MCF7 Lapatinib
0.04
uM
LJP6
 72
hr
 1235 2964 4056 0.7319 0.6659
MCF7 HG-5-88-01
0.04
uM
LJP6
 72
hr
 1235 2625 4056 0.6466 0.5496
MCF7 CP466722
0.04
uM
LJP5
 72
hr
 1235 4851 4267 1.1371 1.1490
MCF7 YM 201636
0.04
uM
LJP5
 72
hr
 1235 4588 4267 1.0741 1.0800
MCF7 Seliciclib
0.04
uM
LJP5
 72
hr
 1235 4831 4267 1.1327 1.1447
MCF7 AZD8055
0.04
uM
LJP6
 72
hr
 1235 1307 4056 0.3227 0.0327
MCF7 JW-7-24-1
0.04
uM
LJP6
 72
hr
 1235 2487 4056 0.6129 0.5030
MCF7 HG-6-64-01
0.04
uM
LJP6
 72
hr
 1235 4834 4056 1.1918 1.2152
MCF7 Sigma A6730
0.04
uM
LJP5
 72
hr
 1235 3330 4267 0.7796 0.7379
MCF7 Saracatinib
0.04
uM
LJP6
 72
hr
 1235 3767 4056 0.9293 0.9157
MCF7 Dasatinib
0.04
uM
LJP5
 72
hr
 1235 2621 4267 0.6157 0.5235
MCF7 Selumetinib
0.04
uM
LJP6
 72
hr
 1235 3986 4056 0.9833 0.9788
MCF7 CGP60474
0.04
uM
LJP5
 72
hr
 1235 4211 4267 0.9887 0.9876
MCF7 Neratinib
0.04
uM
LJP5
 72
hr
 1235 3207 4267 0.7514 0.7040
MCF7 CP724714
0.04
uM
LJP5
 72
hr
 1235 3247 4267 0.7619 0.7178
MCF7 SU11274
0.04
uM
LJP5
 72
hr
 1235 4880 4267 1.1441 1.1561
MCF7 Celastrol
0.04
uM
LJP6
 72
hr
 1235 4494 4056 1.1082 1.1237