LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
SK-BR-3 CGP60474
0.04
uM
LJP5
 72
hr
 1476 4222 3772 1.1193 1.1735
MCF7 NU7441
0.04
uM
LJP5
 72
hr
 1235 4252 4267 0.9971 0.9971
MCF7 PD173074
0.04
uM
LJP6
 72
hr
 1235 4512 4056 1.1128 1.1288
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 72
hr
 868 2868 3556 0.8076 0.8006
MCF7 Seliciclib
0.04
uM
LJP5
 72
hr
 1235 4831 4267 1.1327 1.1447
MCF7 QL-X-138
0.04
uM
LJP6
 72
hr
 1235 1814 4056 0.4463 0.2452
SK-BR-3 Crizotinib
0.04
uM
LJP5
 72
hr
 1476 2870 3772 0.7610 0.6344
MCF7 OSI-027
0.04
uM
LJP6
 72
hr
 1235 3766 4056 0.9282 0.9145
MCF7 PF431396
0.04
uM
LJP5
 72
hr
 1235 3176 4267 0.7446 0.6959
MCF7 XMD11-50
0.04
uM
LJP6
 72
hr
 1235 3637 4056 0.8968 0.8765
MCF7 Vemurafenib
0.04
uM
LJP5
 72
hr
 1235 4219 4267 0.9908 0.9890
MCF7 WZ-4-145
0.04
uM
LJP6
 72
hr
 1235 3090 4056 0.7619 0.7066
MCF7 TWS119
0.04
uM
LJP5
 72
hr
 1235 4758 4267 1.1141 1.1229
MCF7 WYE-125132
0.04
uM
LJP6
 72
hr
 1235 1763 4056 0.4347 0.2305
MCF7 Crizotinib
0.04
uM
LJP5
 72
hr
 1235 3325 4267 0.7794 0.7387
MCF7 PF477736
0.04
uM
LJP5
 72
hr
 1235 2602 4267 0.6100 0.5168
MCF7 HG-6-64-01
0.04
uM
LJP6
 72
hr
 1235 4834 4056 1.1918 1.2152
MCF7 Y39983
0.04
uM
LJP6
 72
hr
 1235 4249 4056 1.0481 1.0557
SK-BR-3 A443654
0.04
uM
LJP6
 72
hr
 1476 1173 3643 0.3221 -0.1636
MCF7 Barasertib
0.04
uM
LJP5
 72
hr
 1235 1732 4267 0.4070 0.2085
MCF7 Pelitinib
0.04
uM
LJP5
 72
hr
 1235 4756 4267 1.1142 1.1242
MCF7 AZD8330
0.04
uM
LJP5
 72
hr
 1235 1989 4267 0.4666 0.3050
MCF7 LDN-193189
0.04
uM
LJP5
 72
hr
 1235 4794 4267 1.1222 1.1302
MDA-MB-231 WYE-125132
0.04
uM
LJP6
 72
hr
 868 2273 3556 0.6400 0.6059
MDA-MB-231 OSI-027
0.04
uM
LJP6
 72
hr
 868 3680 3556 1.0362 1.0355