LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 AZD7762
3.33
uM
LJP6
 72
hr
 868 683 3556 0.1921 -0.1122
MCF 10A PHA-665752
10
uM
LJP5
 72
hr
 513 684 10362 0.0661 0.0614
Hs 578T A443654
10
uM
LJP6
 72
hr
 929 684 3216 0.2125 -0.1579
MCF 10A CGP60474
0.37
uM
LJP5
 72
hr
 513 685 10362 0.0662 0.0689
MCF 10A PD0325901
0.12
uM
LJP6
 72
hr
 513 687 10473 0.0656 0.0682
SK-BR-3 Geldanamycin
10
uM
LJP6
 72
hr
 1476 688 3643 0.1889 -0.4449
MCF 10A Mitoxantrone
0.12
uM
LJP6
 72
hr
 513 690 10473 0.0659 0.0694
MDA-MB-231 Celastrol
3.33
uM
LJP6
 72
hr
 868 692 3556 0.1945 -0.1062
MCF 10A A443654
0.37
uM
LJP6
 72
hr
 513 692 10473 0.0661 0.0704
MCF7 Alvocidib
0.37
uM
LJP6
 72
hr
 1235 694 4056 0.1712 -0.2854
MCF 10A CGP60474
1.11
uM
LJP5
 72
hr
 513 694 10362 0.0670 0.0708
MCF 10A Canertinib
3.33
uM
LJP6
 72
hr
 513 694 10473 0.0663 0.0714
MDA-MB-231 CGP60474
0.37
uM
LJP5
 72
hr
 868 695 3410 0.2044 -0.1065
Hs 578T Foretinib
10
uM
LJP5
 72
hr
 929 697 3237 0.2153 -0.1489
MDA-MB-231 NVP-TAE684
10
uM
LJP6
 72
hr
 868 698 3556 0.1964 -0.1017
MCF 10A GW843682X
3.33
uM
LJP6
 72
hr
 513 701 10473 0.0669 0.0735
MCF7 HG-6-64-01
10
uM
LJP6
 72
hr
 1235 701 4056 0.1733 -0.2817
MCF 10A GW843682X
10
uM
LJP6
 72
hr
 513 701 10473 0.0669 0.0723
MCF 10A AZD 5438
3.33
uM
LJP6
 72
hr
 513 704 10473 0.0672 0.0750
MCF 10A Pictilisib
10
uM
LJP6
 72
hr
 513 704 10473 0.0672 0.0740
MDA-MB-231 SB590885
10
uM
LJP5
 72
hr
 868 706 3410 0.2069 -0.1008
MCF7 Seliciclib
10
uM
LJP5
 72
hr
 1235 706 4267 0.1657 -0.2687
MCF 10A Neratinib
1.11
uM
LJP5
 72
hr
 513 712 10362 0.0688 0.0762
MDA-MB-231 Pelitinib
10
uM
LJP5
 72
hr
 868 713 3410 0.2091 -0.0953
MCF 10A Omipalisib
0.04
uM
LJP6
 72
hr
 513 714 10473 0.0682 0.0784