LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A AZD 5438
1.11
uM
LJP6
 2
J03
 72
hr
 962 645 10740 0.0601 -0.1086
MCF 10A AZD 5438
1.11
uM
LJP6
 3
J03
 72
hr
 962 793 10641 0.0745 -0.0542
MCF 10A AZD 5438
3.33
uM
LJP6
 1
J02
 72
hr
 962 261 10693 0.0244 -0.3131
MCF 10A AZD 5438
3.33
uM
LJP6
 2
J02
 72
hr
 962 234 10740 0.0218 -0.3338
MCF 10A AZD 5438
3.33
uM
LJP6
 3
J02
 72
hr
 962 287 10641 0.0270 -0.2945
MCF 10A AZD 5438
10
uM
LJP6
 1
J01
 72
hr
 962 329 10693 0.0308 -0.2657
MCF 10A AZD 5438
10
uM
LJP6
 2
J01
 72
hr
 962 288 10740 0.0268 -0.2929
MCF 10A AZD 5438
10
uM
LJP6
 3
J01
 72
hr
 962 383 10641 0.0360 -0.2333
MCF 10A Pelitinib
0.04
uM
LJP5
 1
I18
 72
hr
 962 2795 10714 0.2609 0.3589
MCF 10A Pelitinib
0.04
uM
LJP5
 2
I18
 72
hr
 962 2946 10507 0.2804 0.3833
MCF 10A Pelitinib
0.04
uM
LJP5
 3
I18
 72
hr
 962 3753 10315 0.3638 0.4884
MCF 10A Pelitinib
0.12
uM
LJP5
 1
I17
 72
hr
 962 1460 10714 0.1363 0.1274
MCF 10A Pelitinib
0.12
uM
LJP5
 2
I17
 72
hr
 962 1367 10507 0.1301 0.1072
MCF 10A Pelitinib
0.12
uM
LJP5
 3
I17
 72
hr
 962 1375 10315 0.1333 0.1100
MCF 10A Pelitinib
0.37
uM
LJP5
 1
I16
 72
hr
 962 1334 10714 0.1245 0.0985
MCF 10A Pelitinib
0.37
uM
LJP5
 2
I16
 72
hr
 962 1495 10507 0.1423 0.1363
MCF 10A Pelitinib
0.37
uM
LJP5
 3
I16
 72
hr
 962 1191 10315 0.1155 0.0643
MCF 10A Pelitinib
1.11
uM
LJP5
 1
I15
 72
hr
 962 1377 10714 0.1285 0.1086
MCF 10A Pelitinib
1.11
uM
LJP5
 2
I15
 72
hr
 962 1492 10507 0.1420 0.1356
MCF 10A Pelitinib
1.11
uM
LJP5
 3
I15
 72
hr
 962 1348 10315 0.1307 0.1035
MCF 10A Pelitinib
3.33
uM
LJP5
 1
I14
 72
hr
 962 1476 10714 0.1378 0.1310
MCF 10A Pelitinib
3.33
uM
LJP5
 2
I14
 72
hr
 962 1510 10507 0.1437 0.1396
MCF 10A Pelitinib
3.33
uM
LJP5
 3
I14
 72
hr
 962 1320 10315 0.1280 0.0968
MCF 10A Pelitinib
10
uM
LJP5
 1
I13
 72
hr
 962 755 10714 0.0705 -0.0674
MCF 10A Pelitinib
10
uM
LJP5
 2
I13
 72
hr
 962 715 10507 0.0680 -0.0825