LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Pelitinib
10
uM
LJP5
 3
I13
 72
hr
 962 787 10315 0.0763 -0.0570
MCF 10A Luminespib
0.04
uM
LJP5
 1
H18
 72
hr
 962 838 10714 0.0782 -0.0390
MCF 10A Luminespib
0.04
uM
LJP5
 2
H18
 72
hr
 962 863 10507 0.0821 -0.0310
MCF 10A Luminespib
0.04
uM
LJP5
 3
H18
 72
hr
 962 801 10315 0.0777 -0.0522
MCF 10A Luminespib
0.12
uM
LJP5
 1
H17
 72
hr
 962 779 10714 0.0727 -0.0589
MCF 10A Luminespib
0.12
uM
LJP5
 2
H17
 72
hr
 962 823 10507 0.0783 -0.0443
MCF 10A Luminespib
0.12
uM
LJP5
 3
H17
 72
hr
 962 748 10315 0.0725 -0.0709
MCF 10A Luminespib
0.37
uM
LJP5
 1
H16
 72
hr
 962 796 10714 0.0743 -0.0531
MCF 10A Luminespib
0.37
uM
LJP5
 2
H16
 72
hr
 962 889 10507 0.0846 -0.0227
MCF 10A Luminespib
0.37
uM
LJP5
 3
H16
 72
hr
 962 795 10315 0.0771 -0.0542
MCF 10A Luminespib
1.11
uM
LJP5
 1
H15
 72
hr
 962 856 10714 0.0799 -0.0331
MCF 10A Luminespib
1.11
uM
LJP5
 2
H15
 72
hr
 962 837 10507 0.0797 -0.0396
MCF 10A Luminespib
1.11
uM
LJP5
 3
H15
 72
hr
 962 775 10315 0.0751 -0.0613
MCF 10A Luminespib
3.33
uM
LJP5
 1
H14
 72
hr
 962 835 10714 0.0779 -0.0399
MCF 10A Luminespib
3.33
uM
LJP5
 2
H14
 72
hr
 962 802 10507 0.0763 -0.0514
MCF 10A Luminespib
3.33
uM
LJP5
 3
H14
 72
hr
 962 812 10315 0.0787 -0.0484
MCF 10A Luminespib
10
uM
LJP5
 1
H13
 72
hr
 962 887 10714 0.0828 -0.0231
MCF 10A Luminespib
10
uM
LJP5
 2
H13
 72
hr
 962 931 10507 0.0886 -0.0095
MCF 10A Luminespib
10
uM
LJP5
 3
H13
 72
hr
 962 745 10315 0.0722 -0.0720
MCF 10A AZD8330
0.04
uM
LJP5
 1
G24
 72
hr
 962 1627 10714 0.1519 0.1631
MCF 10A AZD8330
0.04
uM
LJP5
 2
G24
 72
hr
 962 1482 10507 0.1410 0.1334
MCF 10A AZD8330
0.04
uM
LJP5
 3
G24
 72
hr
 962 1531 10315 0.1484 0.1454
MCF 10A AZD8330
0.12
uM
LJP5
 1
G23
 72
hr
 962 1576 10714 0.1471 0.1525
MCF 10A AZD8330
0.12
uM
LJP5
 2
G23
 72
hr
 962 1813 10507 0.1725 0.2016
MCF 10A AZD8330
0.12
uM
LJP5
 3
G23
 72
hr
 962 1672 10315 0.1621 0.1752