LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Mitoxantrone
10
uM
LJP5
 1
C19
 72
hr
 962 512 10714 0.0478 -0.1659
MCF 10A Mitoxantrone
10
uM
LJP5
 2
C19
 72
hr
 962 530 10507 0.0504 -0.1588
MCF 10A Mitoxantrone
10
uM
LJP5
 3
C19
 72
hr
 962 485 10315 0.0470 -0.1814
MCF 10A Radicicol
0.04
uM
LJP6
 1
K12
 72
hr
 962 10042 10693 0.9391 0.9641
MCF 10A Radicicol
0.04
uM
LJP6
 2
K12
 72
hr
 962 10317 10740 0.9605 0.9770
MCF 10A Radicicol
0.04
uM
LJP6
 3
K12
 72
hr
 962 9788 10641 0.9198 0.9523
MCF 10A Radicicol
0.04
uM
LJP5
 1
K12
 72
hr
 962 9702 10714 0.9055 0.9437
MCF 10A Radicicol
0.04
uM
LJP5
 2
K12
 72
hr
 962 9954 10507 0.9473 0.9689
MCF 10A Radicicol
0.04
uM
LJP5
 3
K12
 72
hr
 962 9144 10315 0.8865 0.9308
MCF 10A Radicicol
0.12
uM
LJP6
 1
K11
 72
hr
 962 6127 10693 0.5730 0.7038
MCF 10A Radicicol
0.12
uM
LJP6
 2
K11
 72
hr
 962 6826 10740 0.6355 0.7558
MCF 10A Radicicol
0.12
uM
LJP6
 3
K11
 72
hr
 962 6698 10641 0.6294 0.7500
MCF 10A Radicicol
0.12
uM
LJP5
 1
K11
 72
hr
 962 6890 10714 0.6431 0.7615
MCF 10A Radicicol
0.12
uM
LJP5
 2
K11
 72
hr
 962 6886 10507 0.6553 0.7694
MCF 10A Radicicol
0.12
uM
LJP5
 3
K11
 72
hr
 962 5993 10315 0.5810 0.7066
MCF 10A Radicicol
0.37
uM
LJP6
 1
K10
 72
hr
 962 2725 10693 0.2548 0.3494
MCF 10A Radicicol
0.37
uM
LJP6
 2
K10
 72
hr
 962 3113 10740 0.2898 0.4012
MCF 10A Radicicol
0.37
uM
LJP6
 3
K10
 72
hr
 962 2839 10641 0.2668 0.3662
MCF 10A Radicicol
0.37
uM
LJP5
 1
K10
 72
hr
 962 2564 10714 0.2393 0.3256
MCF 10A Radicicol
0.37
uM
LJP5
 2
K10
 72
hr
 962 3313 10507 0.3153 0.4312
MCF 10A Radicicol
0.37
uM
LJP5
 3
K10
 72
hr
 962 2828 10315 0.2742 0.3703
MCF 10A Radicicol
1.11
uM
LJP6
 1
K09
 72
hr
 962 1330 10693 0.1244 0.0977
MCF 10A Radicicol
1.11
uM
LJP6
 2
K09
 72
hr
 962 1290 10740 0.1201 0.0879
MCF 10A Radicicol
1.11
uM
LJP6
 3
K09
 72
hr
 962 1354 10641 0.1272 0.1036
MCF 10A Radicicol
1.11
uM
LJP5
 1
K09
 72
hr
 962 1237 10714 0.1155 0.0749