LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Radicicol
1.11
uM
LJP5
 2
K09
 72
hr
 962 1712 10507 0.1629 0.1818
MCF 10A Radicicol
1.11
uM
LJP5
 3
K09
 72
hr
 962 1152 10315 0.1117 0.0540
MCF 10A Radicicol
3.33
uM
LJP6
 1
K08
 72
hr
 962 755 10693 0.0706 -0.0674
MCF 10A Radicicol
3.33
uM
LJP6
 2
K08
 72
hr
 962 762 10740 0.0709 -0.0648
MCF 10A Radicicol
3.33
uM
LJP6
 3
K08
 72
hr
 962 757 10641 0.0711 -0.0668
MCF 10A Radicicol
3.33
uM
LJP5
 1
K08
 72
hr
 962 709 10714 0.0662 -0.0841
MCF 10A Radicicol
3.33
uM
LJP5
 2
K08
 72
hr
 962 948 10507 0.0902 -0.0043
MCF 10A Radicicol
3.33
uM
LJP5
 3
K08
 72
hr
 962 625 10315 0.0606 -0.1184
MCF 10A Radicicol
10
uM
LJP6
 1
K07
 72
hr
 962 400 10693 0.0374 -0.2232
MCF 10A Radicicol
10
uM
LJP6
 2
K07
 72
hr
 962 389 10740 0.0362 -0.2291
MCF 10A Radicicol
10
uM
LJP6
 3
K07
 72
hr
 962 356 10641 0.0335 -0.2493
MCF 10A Radicicol
10
uM
LJP5
 1
K07
 72
hr
 962 375 10714 0.0350 -0.2374
MCF 10A Radicicol
10
uM
LJP5
 2
K07
 72
hr
 962 570 10507 0.0542 -0.1408
MCF 10A Radicicol
10
uM
LJP5
 3
K07
 72
hr
 962 542 10315 0.0525 -0.1544
MCF 10A Withaferin A
0.04
uM
LJP6
 1
G18
 72
hr
 962 10497 10693 0.9816 0.9893
MCF 10A Withaferin A
0.04
uM
LJP6
 2
G18
 72
hr
 962 10480 10740 0.9757 0.9859
MCF 10A Withaferin A
0.04
uM
LJP6
 3
G18
 72
hr
 962 10682 10641 1.0038 1.0022
MCF 10A Withaferin A
0.04
uM
LJP5
 1
G18
 72
hr
 962 10785 10714 1.0066 1.0038
MCF 10A Withaferin A
0.04
uM
LJP5
 2
G18
 72
hr
 962 10570 10507 1.0059 1.0034
MCF 10A Withaferin A
0.04
uM
LJP5
 3
G18
 72
hr
 962 10454 10315 1.0135 1.0078
MCF 10A Withaferin A
0.12
uM
LJP6
 1
G17
 72
hr
 962 9773 10693 0.9139 0.9488
MCF 10A Withaferin A
0.12
uM
LJP6
 2
G17
 72
hr
 962 9933 10740 0.9248 0.9556
MCF 10A Withaferin A
0.12
uM
LJP6
 3
G17
 72
hr
 962 10448 10641 0.9818 0.9894
MCF 10A Withaferin A
0.12
uM
LJP5
 1
G17
 72
hr
 962 11281 10714 1.0529 1.0299
MCF 10A Withaferin A
0.12
uM
LJP5
 2
G17
 72
hr
 962 10973 10507 1.0443 1.0253