LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Mitoxantrone
0.12
uM
LJP6
 3
C23
 72
hr
 962 1044 10641 0.0981 0.0238
MCF 10A Mitoxantrone
0.12
uM
LJP5
 1
C23
 72
hr
 962 1153 10714 0.1076 0.0534
MCF 10A Mitoxantrone
0.12
uM
LJP5
 2
C23
 72
hr
 962 1032 10507 0.0982 0.0205
MCF 10A Mitoxantrone
0.12
uM
LJP5
 3
C23
 72
hr
 962 956 10315 0.0927 -0.0019
MCF 10A Mitoxantrone
0.37
uM
LJP6
 1
C22
 72
hr
 962 933 10693 0.0872 -0.0088
MCF 10A Mitoxantrone
0.37
uM
LJP6
 2
C22
 72
hr
 962 967 10740 0.0900 0.0014
MCF 10A Mitoxantrone
0.37
uM
LJP6
 3
C22
 72
hr
 962 1018 10641 0.0957 0.0164
MCF 10A Mitoxantrone
0.37
uM
LJP5
 1
C22
 72
hr
 962 1022 10714 0.0954 0.0175
MCF 10A Mitoxantrone
0.37
uM
LJP5
 2
C22
 72
hr
 962 876 10507 0.0834 -0.0268
MCF 10A Mitoxantrone
0.37
uM
LJP5
 3
C22
 72
hr
 962 1031 10315 0.0999 0.0204
MCF 10A Mitoxantrone
1.11
uM
LJP6
 1
C21
 72
hr
 962 826 10693 0.0772 -0.0430
MCF 10A Mitoxantrone
1.11
uM
LJP6
 2
C21
 72
hr
 962 839 10740 0.0781 -0.0386
MCF 10A Mitoxantrone
1.11
uM
LJP6
 3
C21
 72
hr
 962 792 10641 0.0744 -0.0546
MCF 10A Mitoxantrone
1.11
uM
LJP5
 1
C21
 72
hr
 962 862 10714 0.0805 -0.0311
MCF 10A Mitoxantrone
1.11
uM
LJP5
 2
C21
 72
hr
 962 945 10507 0.0899 -0.0052
MCF 10A Mitoxantrone
1.11
uM
LJP5
 3
C21
 72
hr
 962 845 10315 0.0819 -0.0372
MCF 10A Mitoxantrone
3.33
uM
LJP6
 1
C20
 72
hr
 962 451 10693 0.0422 -0.1960
MCF 10A Mitoxantrone
3.33
uM
LJP6
 2
C20
 72
hr
 962 409 10740 0.0381 -0.2179
MCF 10A Mitoxantrone
3.33
uM
LJP6
 3
C20
 72
hr
 962 521 10641 0.0490 -0.1622
MCF 10A Mitoxantrone
3.33
uM
LJP5
 1
C20
 72
hr
 962 495 10714 0.0462 -0.1740
MCF 10A Mitoxantrone
3.33
uM
LJP5
 2
C20
 72
hr
 962 324 10507 0.0308 -0.2706
MCF 10A Mitoxantrone
3.33
uM
LJP5
 3
C20
 72
hr
 962 323 10315 0.0313 -0.2731
MCF 10A Mitoxantrone
10
uM
LJP6
 1
C19
 72
hr
 962 484 10693 0.0453 -0.1794
MCF 10A Mitoxantrone
10
uM
LJP6
 2
C19
 72
hr
 962 572 10740 0.0533 -0.1388
MCF 10A Mitoxantrone
10
uM
LJP6
 3
C19
 72
hr
 962 601 10641 0.0565 -0.1269