LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A GDC-0980
0.04
uM
LJP5
 2
K24
 72
hr
 962 8811 10507 0.8385 0.9004
MCF 10A GDC-0980
0.04
uM
LJP5
 3
K24
 72
hr
 962 8107 10315 0.7859 0.8641
MCF 10A GDC-0980
0.12
uM
LJP5
 1
K23
 72
hr
 962 4218 10714 0.3937 0.5297
MCF 10A GDC-0980
0.12
uM
LJP5
 2
K23
 72
hr
 962 4650 10507 0.4425 0.5790
MCF 10A GDC-0980
0.12
uM
LJP5
 3
K23
 72
hr
 962 3954 10315 0.3833 0.5113
MCF 10A GDC-0980
0.37
uM
LJP5
 1
K22
 72
hr
 962 1875 10714 0.1750 0.2115
MCF 10A GDC-0980
0.37
uM
LJP5
 2
K22
 72
hr
 962 1893 10507 0.1802 0.2168
MCF 10A GDC-0980
0.37
uM
LJP5
 3
K22
 72
hr
 962 1931 10315 0.1872 0.2257
MCF 10A GDC-0980
1.11
uM
LJP5
 1
K21
 72
hr
 962 1411 10714 0.1317 0.1164
MCF 10A GDC-0980
1.11
uM
LJP5
 2
K21
 72
hr
 962 1470 10507 0.1399 0.1308
MCF 10A GDC-0980
1.11
uM
LJP5
 3
K21
 72
hr
 962 1310 10315 0.1270 0.0944
MCF 10A GDC-0980
3.33
uM
LJP5
 1
K20
 72
hr
 962 1205 10714 0.1125 0.0669
MCF 10A GDC-0980
3.33
uM
LJP5
 2
K20
 72
hr
 962 1292 10507 0.1230 0.0892
MCF 10A GDC-0980
3.33
uM
LJP5
 3
K20
 72
hr
 962 1267 10315 0.1228 0.0837
MCF 10A GDC-0980
10
uM
LJP5
 1
K19
 72
hr
 962 1010 10714 0.0943 0.0141
MCF 10A GDC-0980
10
uM
LJP5
 2
K19
 72
hr
 962 893 10507 0.0850 -0.0214
MCF 10A GDC-0980
10
uM
LJP5
 3
K19
 72
hr
 962 960 10315 0.0931 -0.0007
MCF 10A Mitoxantrone
0.04
uM
LJP6
 1
C24
 72
hr
 962 2021 10693 0.1890 0.2381
MCF 10A Mitoxantrone
0.04
uM
LJP6
 2
C24
 72
hr
 962 1967 10740 0.1831 0.2281
MCF 10A Mitoxantrone
0.04
uM
LJP6
 3
C24
 72
hr
 962 2152 10641 0.2022 0.2613
MCF 10A Mitoxantrone
0.04
uM
LJP5
 1
C24
 72
hr
 962 2375 10714 0.2217 0.2968
MCF 10A Mitoxantrone
0.04
uM
LJP5
 2
C24
 72
hr
 962 2280 10507 0.2170 0.2842
MCF 10A Mitoxantrone
0.04
uM
LJP5
 3
C24
 72
hr
 962 2062 10315 0.1999 0.2495
MCF 10A Mitoxantrone
0.12
uM
LJP6
 1
C23
 72
hr
 962 1035 10693 0.0968 0.0212
MCF 10A Mitoxantrone
0.12
uM
LJP6
 2
C23
 72
hr
 962 994 10740 0.0925 0.0094