LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Dactolisib
3.33
uM
LJP5
 1
M14
 72
hr
 962 1302 10714 0.1215 0.0909
MCF 10A Dactolisib
3.33
uM
LJP5
 2
M14
 72
hr
 962 1566 10507 0.1490 0.1517
MCF 10A Dactolisib
3.33
uM
LJP5
 3
M14
 72
hr
 962 1440 10315 0.1396 0.1250
MCF 10A Dactolisib
10
uM
LJP5
 1
M13
 72
hr
 962 1678 10714 0.1566 0.1735
MCF 10A Dactolisib
10
uM
LJP5
 2
M13
 72
hr
 962 1686 10507 0.1605 0.1766
MCF 10A Dactolisib
10
uM
LJP5
 3
M13
 72
hr
 962 1596 10315 0.1547 0.1594
MCF 10A Alpelisib
0.04
uM
LJP5
 1
N06
 72
hr
 962 10549 10714 0.9846 0.9911
MCF 10A Alpelisib
0.04
uM
LJP5
 2
N06
 72
hr
 962 10984 10507 1.0453 1.0259
MCF 10A Alpelisib
0.04
uM
LJP5
 3
N06
 72
hr
 962 10053 10315 0.9746 0.9850
MCF 10A Alpelisib
0.12
uM
LJP5
 1
N05
 72
hr
 962 10193 10714 0.9514 0.9715
MCF 10A Alpelisib
0.12
uM
LJP5
 2
N05
 72
hr
 962 10598 10507 1.0086 1.0050
MCF 10A Alpelisib
0.12
uM
LJP5
 3
N05
 72
hr
 962 10044 10315 0.9737 0.9845
MCF 10A Alpelisib
0.37
uM
LJP5
 1
N04
 72
hr
 962 9822 10714 0.9167 0.9506
MCF 10A Alpelisib
0.37
uM
LJP5
 2
N04
 72
hr
 962 9962 10507 0.9481 0.9693
MCF 10A Alpelisib
0.37
uM
LJP5
 3
N04
 72
hr
 962 9625 10315 0.9331 0.9599
MCF 10A Alpelisib
1.11
uM
LJP5
 1
N03
 72
hr
 962 9031 10714 0.8429 0.9041
MCF 10A Alpelisib
1.11
uM
LJP5
 2
N03
 72
hr
 962 9272 10507 0.8824 0.9287
MCF 10A Alpelisib
1.11
uM
LJP5
 3
N03
 72
hr
 962 9109 10315 0.8831 0.9286
MCF 10A Alpelisib
3.33
uM
LJP5
 1
N02
 72
hr
 962 8312 10714 0.7758 0.8592
MCF 10A Alpelisib
3.33
uM
LJP5
 2
N02
 72
hr
 962 8576 10507 0.8162 0.8856
MCF 10A Alpelisib
3.33
uM
LJP5
 3
N02
 72
hr
 962 7900 10315 0.7659 0.8500
MCF 10A Alpelisib
10
uM
LJP5
 1
N01
 72
hr
 962 4478 10714 0.4180 0.5562
MCF 10A Alpelisib
10
uM
LJP5
 2
N01
 72
hr
 962 4862 10507 0.4627 0.5995
MCF 10A Alpelisib
10
uM
LJP5
 3
N01
 72
hr
 962 4279 10315 0.4148 0.5466
MCF 10A GDC-0980
0.04
uM
LJP5
 1
K24
 72
hr
 962 8799 10714 0.8213 0.8899