LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Foretinib
0.12
uM
LJP5
 1
H11
 72
hr
 962 10324 10714 0.9636 0.9788
MCF 10A Foretinib
0.12
uM
LJP5
 2
H11
 72
hr
 962 9716 10507 0.9246 0.9551
MCF 10A Foretinib
0.12
uM
LJP5
 3
H11
 72
hr
 962 9498 10315 0.9208 0.9523
MCF 10A Foretinib
0.37
uM
LJP5
 1
H10
 72
hr
 962 8642 10714 0.8066 0.8801
MCF 10A Foretinib
0.37
uM
LJP5
 2
H10
 72
hr
 962 8357 10507 0.7953 0.8715
MCF 10A Foretinib
0.37
uM
LJP5
 3
H10
 72
hr
 962 8160 10315 0.7911 0.8676
MCF 10A Foretinib
1.11
uM
LJP5
 1
H09
 72
hr
 962 3011 10714 0.2810 0.3883
MCF 10A Foretinib
1.11
uM
LJP5
 2
H09
 72
hr
 962 2801 10507 0.2666 0.3632
MCF 10A Foretinib
1.11
uM
LJP5
 3
H09
 72
hr
 962 2456 10315 0.2381 0.3150
MCF 10A Foretinib
3.33
uM
LJP5
 1
H08
 72
hr
 962 1584 10714 0.1478 0.1542
MCF 10A Foretinib
3.33
uM
LJP5
 2
H08
 72
hr
 962 1460 10507 0.1389 0.1285
MCF 10A Foretinib
3.33
uM
LJP5
 3
H08
 72
hr
 962 1427 10315 0.1383 0.1221
MCF 10A Foretinib
10
uM
LJP5
 1
H07
 72
hr
 962 943 10714 0.0880 -0.0058
MCF 10A Foretinib
10
uM
LJP5
 2
H07
 72
hr
 962 871 10507 0.0829 -0.0284
MCF 10A Foretinib
10
uM
LJP5
 3
H07
 72
hr
 962 978 10315 0.0948 0.0048
MCF 10A AZD 5438
0.04
uM
LJP6
 1
J06
 72
hr
 962 9656 10693 0.9030 0.9421
MCF 10A AZD 5438
0.04
uM
LJP6
 2
J06
 72
hr
 962 9634 10740 0.8970 0.9385
MCF 10A AZD 5438
0.04
uM
LJP6
 3
J06
 72
hr
 962 9569 10641 0.8992 0.9396
MCF 10A AZD 5438
0.12
uM
LJP6
 1
J05
 72
hr
 962 7290 10693 0.6817 0.7912
MCF 10A AZD 5438
0.12
uM
LJP6
 2
J05
 72
hr
 962 7092 10740 0.6603 0.7752
MCF 10A AZD 5438
0.12
uM
LJP6
 3
J05
 72
hr
 962 6622 10641 0.6223 0.7443
MCF 10A AZD 5438
0.37
uM
LJP6
 1
J04
 72
hr
 962 2405 10693 0.2249 0.3017
MCF 10A AZD 5438
0.37
uM
LJP6
 2
J04
 72
hr
 962 2240 10740 0.2086 0.2748
MCF 10A AZD 5438
0.37
uM
LJP6
 3
J04
 72
hr
 962 2579 10641 0.2424 0.3289
MCF 10A AZD 5438
1.11
uM
LJP6
 1
J03
 72
hr
 962 693 10693 0.0648 -0.0901