LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A GSK 690693
0.12
uM
LJP5
 3
F23
 72
hr
 962 9634 10315 0.9340 0.9605
MCF 10A GSK 690693
0.37
uM
LJP5
 1
F22
 72
hr
 962 8493 10714 0.7927 0.8707
MCF 10A GSK 690693
0.37
uM
LJP5
 2
F22
 72
hr
 962 9124 10507 0.8683 0.9198
MCF 10A GSK 690693
0.37
uM
LJP5
 3
F22
 72
hr
 962 8708 10315 0.8442 0.9034
MCF 10A GSK 690693
1.11
uM
LJP5
 1
F21
 72
hr
 962 8455 10714 0.7892 0.8683
MCF 10A GSK 690693
1.11
uM
LJP5
 2
F21
 72
hr
 962 8597 10507 0.8182 0.8869
MCF 10A GSK 690693
1.11
uM
LJP5
 3
F21
 72
hr
 962 7977 10315 0.7733 0.8553
MCF 10A GSK 690693
3.33
uM
LJP5
 1
F20
 72
hr
 962 8344 10714 0.7788 0.8612
MCF 10A GSK 690693
3.33
uM
LJP5
 2
F20
 72
hr
 962 8113 10507 0.7721 0.8555
MCF 10A GSK 690693
3.33
uM
LJP5
 3
F20
 72
hr
 962 8149 10315 0.7900 0.8669
MCF 10A GSK 690693
10
uM
LJP5
 1
F19
 72
hr
 962 8722 10714 0.8141 0.8851
MCF 10A GSK 690693
10
uM
LJP5
 2
F19
 72
hr
 962 8722 10507 0.8301 0.8949
MCF 10A GSK 690693
10
uM
LJP5
 3
F19
 72
hr
 962 8674 10315 0.8409 0.9013
MCF 10A SNS-032
0.04
uM
LJP6
 1
H18
 72
hr
 962 9723 10693 0.9092 0.9460
MCF 10A SNS-032
0.04
uM
LJP6
 2
H18
 72
hr
 962 9926 10740 0.9241 0.9552
MCF 10A SNS-032
0.04
uM
LJP6
 3
H18
 72
hr
 962 9867 10641 0.9272 0.9569
MCF 10A SNS-032
0.12
uM
LJP6
 1
H17
 72
hr
 962 1205 10693 0.1127 0.0669
MCF 10A SNS-032
0.12
uM
LJP6
 2
H17
 72
hr
 962 1194 10740 0.1112 0.0640
MCF 10A SNS-032
0.12
uM
LJP6
 3
H17
 72
hr
 962 1229 10641 0.1155 0.0731
MCF 10A SNS-032
0.37
uM
LJP6
 1
H16
 72
hr
 962 441 10693 0.0412 -0.2011
MCF 10A SNS-032
0.37
uM
LJP6
 2
H16
 72
hr
 962 449 10740 0.0418 -0.1967
MCF 10A SNS-032
0.37
uM
LJP6
 3
H16
 72
hr
 962 466 10641 0.0438 -0.1887
MCF 10A SNS-032
1.11
uM
LJP6
 1
H15
 72
hr
 962 301 10693 0.0281 -0.2843
MCF 10A SNS-032
1.11
uM
LJP6
 2
H15
 72
hr
 962 254 10740 0.0236 -0.3179
MCF 10A SNS-032
1.11
uM
LJP6
 3
H15
 72
hr
 962 329 10641 0.0309 -0.2662