LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A PI103
10
uM
LJP6
 2
I13
 72
hr
 962 1020 10740 0.0950 0.0169
MCF 10A PI103
10
uM
LJP6
 3
I13
 72
hr
 962 1195 10641 0.1123 0.0645
MCF 10A Dovitinib
0.04
uM
LJP5
 1
E24
 72
hr
 962 10639 10714 0.9930 0.9960
MCF 10A Dovitinib
0.04
uM
LJP5
 2
E24
 72
hr
 962 10934 10507 1.0406 1.0232
MCF 10A Dovitinib
0.04
uM
LJP5
 3
E24
 72
hr
 962 9878 10315 0.9576 0.9749
MCF 10A Dovitinib
0.12
uM
LJP5
 1
E23
 72
hr
 962 9359 10714 0.8735 0.9237
MCF 10A Dovitinib
0.12
uM
LJP5
 2
E23
 72
hr
 962 9658 10507 0.9191 0.9517
MCF 10A Dovitinib
0.12
uM
LJP5
 3
E23
 72
hr
 962 9263 10315 0.8980 0.9381
MCF 10A Dovitinib
0.37
uM
LJP5
 1
E22
 72
hr
 962 3581 10714 0.3342 0.4593
MCF 10A Dovitinib
0.37
uM
LJP5
 2
E22
 72
hr
 962 3526 10507 0.3356 0.4573
MCF 10A Dovitinib
0.37
uM
LJP5
 3
E22
 72
hr
 962 4623 10315 0.4482 0.5819
MCF 10A Dovitinib
1.11
uM
LJP5
 1
E21
 72
hr
 962 1588 10714 0.1482 0.1550
MCF 10A Dovitinib
1.11
uM
LJP5
 2
E21
 72
hr
 962 1815 10507 0.1727 0.2020
MCF 10A Dovitinib
1.11
uM
LJP5
 3
E21
 72
hr
 962 1626 10315 0.1576 0.1657
MCF 10A Dovitinib
3.33
uM
LJP5
 1
E20
 72
hr
 962 1150 10714 0.1073 0.0526
MCF 10A Dovitinib
3.33
uM
LJP5
 2
E20
 72
hr
 962 1099 10507 0.1046 0.0393
MCF 10A Dovitinib
3.33
uM
LJP5
 3
E20
 72
hr
 962 1175 10315 0.1139 0.0601
MCF 10A Dovitinib
10
uM
LJP5
 1
E19
 72
hr
 962 963 10714 0.0899 0.0003
MCF 10A Dovitinib
10
uM
LJP5
 2
E19
 72
hr
 962 950 10507 0.0904 -0.0037
MCF 10A Dovitinib
10
uM
LJP5
 3
E19
 72
hr
 962 852 10315 0.0826 -0.0349
MCF 10A GSK 690693
0.04
uM
LJP5
 1
F24
 72
hr
 962 10632 10714 0.9924 0.9956
MCF 10A GSK 690693
0.04
uM
LJP5
 2
F24
 72
hr
 962 10534 10507 1.0025 1.0014
MCF 10A GSK 690693
0.04
uM
LJP5
 3
F24
 72
hr
 962 10281 10315 0.9967 0.9981
MCF 10A GSK 690693
0.12
uM
LJP5
 1
F23
 72
hr
 962 9559 10714 0.8922 0.9355
MCF 10A GSK 690693
0.12
uM
LJP5
 2
F23
 72
hr
 962 10207 10507 0.9714 0.9832