LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A PD0325901
1.11
uM
LJP6
 1
E03
 72
hr
 962 1317 10693 0.1232 0.0946
MCF 10A PD0325901
1.11
uM
LJP6
 2
E03
 72
hr
 962 1495 10740 0.1392 0.1350
MCF 10A PD0325901
1.11
uM
LJP6
 3
E03
 72
hr
 962 1297 10641 0.1219 0.0899
MCF 10A PD0325901
1.11
uM
LJP5
 1
C03
 72
hr
 962 1993 10714 0.1860 0.2330
MCF 10A PD0325901
1.11
uM
LJP5
 2
C03
 72
hr
 962 1668 10507 0.1587 0.1730
MCF 10A PD0325901
1.11
uM
LJP5
 3
C03
 72
hr
 962 1770 10315 0.1716 0.1950
MCF 10A PD0325901
3.33
uM
LJP6
 1
E02
 72
hr
 962 1072 10693 0.1003 0.0316
MCF 10A PD0325901
3.33
uM
LJP6
 2
E02
 72
hr
 962 1104 10740 0.1028 0.0403
MCF 10A PD0325901
3.33
uM
LJP6
 3
E02
 72
hr
 962 1224 10641 0.1150 0.0719
MCF 10A PD0325901
3.33
uM
LJP5
 1
C02
 72
hr
 962 1748 10714 0.1632 0.1873
MCF 10A PD0325901
3.33
uM
LJP5
 2
C02
 72
hr
 962 1656 10507 0.1576 0.1705
MCF 10A PD0325901
3.33
uM
LJP5
 3
C02
 72
hr
 962 2198 10315 0.2131 0.2730
MCF 10A PD0325901
10
uM
LJP6
 1
E01
 72
hr
 962 1098 10693 0.1027 0.0387
MCF 10A PD0325901
10
uM
LJP6
 2
E01
 72
hr
 962 1234 10740 0.1149 0.0741
MCF 10A PD0325901
10
uM
LJP6
 3
E01
 72
hr
 962 1079 10641 0.1014 0.0336
MCF 10A PD0325901
10
uM
LJP5
 1
C01
 72
hr
 962 1512 10714 0.1411 0.1388
MCF 10A PD0325901
10
uM
LJP5
 2
C01
 72
hr
 962 1620 10507 0.1542 0.1631
MCF 10A PD0325901
10
uM
LJP5
 3
C01
 72
hr
 962 1670 10315 0.1619 0.1748
MCF 10A Geldanamycin
0.04
uM
LJP6
 1
O06
 72
hr
 962 1188 10693 0.1111 0.0626
MCF 10A Geldanamycin
0.04
uM
LJP6
 2
O06
 72
hr
 962 1255 10740 0.1168 0.0793
MCF 10A Geldanamycin
0.04
uM
LJP6
 3
O06
 72
hr
 962 1244 10641 0.1169 0.0769
MCF 10A Geldanamycin
0.04
uM
LJP5
 1
O06
 72
hr
 962 1805 10714 0.1685 0.1983
MCF 10A Geldanamycin
0.04
uM
LJP5
 2
O06
 72
hr
 962 1653 10507 0.1573 0.1699
MCF 10A Geldanamycin
0.04
uM
LJP5
 3
O06
 72
hr
 962 1729 10315 0.1676 0.1868
MCF 10A Geldanamycin
0.12
uM
LJP6
 1
O05
 72
hr
 962 827 10693 0.0773 -0.0426