LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A SNS-032
3.33
uM
LJP6
 1
H14
 72
hr
 962 196 10693 0.0183 -0.3674
MCF 10A SNS-032
3.33
uM
LJP6
 2
H14
 72
hr
 962 336 10740 0.0313 -0.2609
MCF 10A SNS-032
3.33
uM
LJP6
 3
H14
 72
hr
 962 289 10641 0.0272 -0.2931
MCF 10A SNS-032
10
uM
LJP6
 1
H13
 72
hr
 962 256 10693 0.0239 -0.3169
MCF 10A SNS-032
10
uM
LJP6
 2
H13
 72
hr
 962 490 10740 0.0456 -0.1762
MCF 10A SNS-032
10
uM
LJP6
 3
H13
 72
hr
 962 228 10641 0.0214 -0.3398
MCF 10A Afatinib
0.04
uM
LJP6
 1
G24
 72
hr
 962 1738 10693 0.1625 0.1855
MCF 10A Afatinib
0.04
uM
LJP6
 2
G24
 72
hr
 962 1652 10740 0.1538 0.1680
MCF 10A Afatinib
0.04
uM
LJP6
 3
G24
 72
hr
 962 1751 10641 0.1645 0.1885
MCF 10A Afatinib
0.12
uM
LJP6
 1
G23
 72
hr
 962 1452 10693 0.1358 0.1257
MCF 10A Afatinib
0.12
uM
LJP6
 2
G23
 72
hr
 962 1603 10740 0.1492 0.1580
MCF 10A Afatinib
0.12
uM
LJP6
 3
G23
 72
hr
 962 1509 10641 0.1418 0.1386
MCF 10A Afatinib
0.37
uM
LJP6
 1
G22
 72
hr
 962 1496 10693 0.1399 0.1355
MCF 10A Afatinib
0.37
uM
LJP6
 2
G22
 72
hr
 962 1347 10740 0.1254 0.1015
MCF 10A Afatinib
0.37
uM
LJP6
 3
G22
 72
hr
 962 1373 10641 0.1290 0.1080
MCF 10A Afatinib
1.11
uM
LJP6
 1
G21
 72
hr
 962 1309 10693 0.1224 0.0926
MCF 10A Afatinib
1.11
uM
LJP6
 2
G21
 72
hr
 962 1443 10740 0.1344 0.1235
MCF 10A Afatinib
1.11
uM
LJP6
 3
G21
 72
hr
 962 1397 10641 0.1313 0.1135
MCF 10A Afatinib
3.33
uM
LJP6
 1
G20
 72
hr
 962 1492 10693 0.1395 0.1346
MCF 10A Afatinib
3.33
uM
LJP6
 2
G20
 72
hr
 962 1510 10740 0.1406 0.1382
MCF 10A Afatinib
3.33
uM
LJP6
 3
G20
 72
hr
 962 1449 10641 0.1362 0.1253
MCF 10A Afatinib
10
uM
LJP6
 1
G19
 72
hr
 962 1229 10693 0.1149 0.0730
MCF 10A Afatinib
10
uM
LJP6
 2
G19
 72
hr
 962 1274 10740 0.1186 0.0840
MCF 10A Afatinib
10
uM
LJP6
 3
G19
 72
hr
 962 1178 10641 0.1107 0.0601
MCF 10A GSK1904529A
0.04
uM
LJP6
 1
H24
 72
hr
 962 9087 10693 0.8498 0.9084