LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Geldanamycin
10
uM
LJP6
 3
O01
 72
hr
 962 380 10641 0.0357 -0.2350
MCF 10A Geldanamycin
10
uM
LJP5
 1
O01
 72
hr
 962 633 10714 0.0591 -0.1135
MCF 10A Geldanamycin
10
uM
LJP5
 2
O01
 72
hr
 962 604 10507 0.0575 -0.1263
MCF 10A Geldanamycin
10
uM
LJP5
 3
O01
 72
hr
 962 779 10315 0.0755 -0.0598
MCF 10A YM 201636
0.04
uM
LJP5
 1
N12
 72
hr
 962 10645 10714 0.9936 0.9963
MCF 10A YM 201636
0.04
uM
LJP5
 2
N12
 72
hr
 962 10864 10507 1.0339 1.0194
MCF 10A YM 201636
0.04
uM
LJP5
 3
N12
 72
hr
 962 10476 10315 1.0156 1.0091
MCF 10A YM 201636
0.12
uM
LJP5
 1
N11
 72
hr
 962 10440 10714 0.9744 0.9852
MCF 10A YM 201636
0.12
uM
LJP5
 2
N11
 72
hr
 962 10749 10507 1.0229 1.0132
MCF 10A YM 201636
0.12
uM
LJP5
 3
N11
 72
hr
 962 10139 10315 0.9829 0.9900
MCF 10A YM 201636
0.37
uM
LJP5
 1
N10
 72
hr
 962 10273 10714 0.9588 0.9760
MCF 10A YM 201636
0.37
uM
LJP5
 2
N10
 72
hr
 962 10236 10507 0.9741 0.9849
MCF 10A YM 201636
0.37
uM
LJP5
 3
N10
 72
hr
 962 9725 10315 0.9428 0.9659
MCF 10A YM 201636
1.11
uM
LJP5
 1
N09
 72
hr
 962 7728 10714 0.7213 0.8206
MCF 10A YM 201636
1.11
uM
LJP5
 2
N09
 72
hr
 962 8358 10507 0.7954 0.8716
MCF 10A YM 201636
1.11
uM
LJP5
 3
N09
 72
hr
 962 7394 10315 0.7168 0.8146
MCF 10A YM 201636
3.33
uM
LJP5
 1
N08
 72
hr
 962 5871 10714 0.5480 0.6823
MCF 10A YM 201636
3.33
uM
LJP5
 2
N08
 72
hr
 962 6416 10507 0.6106 0.7335
MCF 10A YM 201636
3.33
uM
LJP5
 3
N08
 72
hr
 962 5932 10315 0.5751 0.7015
MCF 10A YM 201636
10
uM
LJP5
 1
N07
 72
hr
 962 2569 10714 0.2398 0.3264
MCF 10A YM 201636
10
uM
LJP5
 2
N07
 72
hr
 962 3061 10507 0.2913 0.3987
MCF 10A YM 201636
10
uM
LJP5
 3
N07
 72
hr
 962 2381 10315 0.2308 0.3031
MCF 10A TWS119
0.04
uM
LJP5
 1
M06
 72
hr
 962 10846 10714 1.0123 1.0071
MCF 10A TWS119
0.04
uM
LJP5
 2
M06
 72
hr
 962 10494 10507 0.9987 0.9992
MCF 10A TWS119
0.04
uM
LJP5
 3
M06
 72
hr
 962 10311 10315 0.9996 0.9998