LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Barasertib
1.11
uM
LJP5
 2
D09
 72
hr
 962 1514 10507 0.1441 0.1405
MCF 10A Barasertib
1.11
uM
LJP5
 3
D09
 72
hr
 962 1437 10315 0.1393 0.1244
MCF 10A Barasertib
3.33
uM
LJP5
 1
D08
 72
hr
 962 1543 10714 0.1440 0.1455
MCF 10A Barasertib
3.33
uM
LJP5
 2
D08
 72
hr
 962 1426 10507 0.1357 0.1208
MCF 10A Barasertib
3.33
uM
LJP5
 3
D08
 72
hr
 962 1513 10315 0.1467 0.1414
MCF 10A Barasertib
10
uM
LJP5
 1
D07
 72
hr
 962 1598 10714 0.1492 0.1571
MCF 10A Barasertib
10
uM
LJP5
 2
D07
 72
hr
 962 1227 10507 0.1168 0.0730
MCF 10A Barasertib
10
uM
LJP5
 3
D07
 72
hr
 962 1571 10315 0.1523 0.1540
MCF 10A Vemurafenib
0.04
uM
LJP5
 1
C18
 72
hr
 962 10751 10714 1.0035 1.0020
MCF 10A Vemurafenib
0.04
uM
LJP5
 2
C18
 72
hr
 962 10168 10507 0.9677 0.9810
MCF 10A Vemurafenib
0.04
uM
LJP5
 3
C18
 72
hr
 962 10278 10315 0.9964 0.9979
MCF 10A Vemurafenib
0.12
uM
LJP5
 1
C17
 72
hr
 962 10271 10714 0.9587 0.9759
MCF 10A Vemurafenib
0.12
uM
LJP5
 2
C17
 72
hr
 962 10387 10507 0.9885 0.9933
MCF 10A Vemurafenib
0.12
uM
LJP5
 3
C17
 72
hr
 962 10057 10315 0.9750 0.9852
MCF 10A Vemurafenib
0.37
uM
LJP5
 1
C16
 72
hr
 962 10663 10714 0.9952 0.9973
MCF 10A Vemurafenib
0.37
uM
LJP5
 2
C16
 72
hr
 962 10191 10507 0.9699 0.9823
MCF 10A Vemurafenib
0.37
uM
LJP5
 3
C16
 72
hr
 962 10075 10315 0.9767 0.9863
MCF 10A Vemurafenib
1.11
uM
LJP5
 1
C15
 72
hr
 962 10363 10714 0.9672 0.9809
MCF 10A Vemurafenib
1.11
uM
LJP5
 2
C15
 72
hr
 962 10240 10507 0.9745 0.9851
MCF 10A Vemurafenib
1.11
uM
LJP5
 3
C15
 72
hr
 962 9723 10315 0.9426 0.9657
MCF 10A Vemurafenib
3.33
uM
LJP5
 1
C14
 72
hr
 962 8949 10714 0.8353 0.8991
MCF 10A Vemurafenib
3.33
uM
LJP5
 2
C14
 72
hr
 962 8336 10507 0.7933 0.8701
MCF 10A Vemurafenib
3.33
uM
LJP5
 3
C14
 72
hr
 962 8922 10315 0.8649 0.9170
MCF 10A Vemurafenib
10
uM
LJP5
 1
C13
 72
hr
 962 4279 10714 0.3994 0.5360
MCF 10A Vemurafenib
10
uM
LJP5
 2
C13
 72
hr
 962 4469 10507 0.4253 0.5609