LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Vemurafenib | 10 | uM | LJP5 | 3 | C13 | 72 | hr | 962 | 3748 | 10315 | 0.3634 | 0.4878 |
| MCF 10A | Enzastaurin | 0.04 | uM | LJP5 | 1 | D18 | 72 | hr | 962 | 10942 | 10714 | 1.0213 | 1.0121 |
| MCF 10A | Enzastaurin | 0.04 | uM | LJP5 | 2 | D18 | 72 | hr | 962 | 10816 | 10507 | 1.0293 | 1.0168 |
| MCF 10A | Enzastaurin | 0.04 | uM | LJP5 | 3 | D18 | 72 | hr | 962 | 10516 | 10315 | 1.0195 | 1.0113 |
| MCF 10A | Enzastaurin | 0.12 | uM | LJP5 | 1 | D17 | 72 | hr | 962 | 11019 | 10714 | 1.0285 | 1.0162 |
| MCF 10A | Enzastaurin | 0.12 | uM | LJP5 | 2 | D17 | 72 | hr | 962 | 10716 | 10507 | 1.0198 | 1.0114 |
| MCF 10A | Enzastaurin | 0.12 | uM | LJP5 | 3 | D17 | 72 | hr | 962 | 10552 | 10315 | 1.0230 | 1.0133 |
| MCF 10A | Enzastaurin | 0.37 | uM | LJP5 | 1 | D16 | 72 | hr | 962 | 11161 | 10714 | 1.0417 | 1.0236 |
| MCF 10A | Enzastaurin | 0.37 | uM | LJP5 | 2 | D16 | 72 | hr | 962 | 10571 | 10507 | 1.0060 | 1.0035 |
| MCF 10A | Enzastaurin | 0.37 | uM | LJP5 | 3 | D16 | 72 | hr | 962 | 10821 | 10315 | 1.0490 | 1.0282 |
| MCF 10A | Enzastaurin | 1.11 | uM | LJP5 | 1 | D15 | 72 | hr | 962 | 11719 | 10714 | 1.0938 | 1.0522 |
| MCF 10A | Enzastaurin | 1.11 | uM | LJP5 | 2 | D15 | 72 | hr | 962 | 10932 | 10507 | 1.0404 | 1.0231 |
| MCF 10A | Enzastaurin | 1.11 | uM | LJP5 | 3 | D15 | 72 | hr | 962 | 11108 | 10315 | 1.0769 | 1.0437 |
| MCF 10A | Enzastaurin | 3.33 | uM | LJP5 | 1 | D14 | 72 | hr | 962 | 11827 | 10714 | 1.1039 | 1.0577 |
| MCF 10A | Enzastaurin | 3.33 | uM | LJP5 | 2 | D14 | 72 | hr | 962 | 11536 | 10507 | 1.0978 | 1.0549 |
| MCF 10A | Enzastaurin | 3.33 | uM | LJP5 | 3 | D14 | 72 | hr | 962 | 11353 | 10315 | 1.1006 | 1.0568 |
| MCF 10A | Enzastaurin | 10 | uM | LJP5 | 1 | D13 | 72 | hr | 962 | 11595 | 10714 | 1.0822 | 1.0460 |
| MCF 10A | Enzastaurin | 10 | uM | LJP5 | 2 | D13 | 72 | hr | 962 | 10874 | 10507 | 1.0348 | 1.0200 |
| MCF 10A | Enzastaurin | 10 | uM | LJP5 | 3 | D13 | 72 | hr | 962 | 10901 | 10315 | 1.0568 | 1.0325 |
| MCF 10A | Palbociclib | 0.04 | uM | LJP6 | 1 | E18 | 72 | hr | 962 | 7338 | 10693 | 0.6862 | 0.7946 |
| MCF 10A | Palbociclib | 0.04 | uM | LJP6 | 2 | E18 | 72 | hr | 962 | 7226 | 10740 | 0.6728 | 0.7847 |
| MCF 10A | Palbociclib | 0.04 | uM | LJP6 | 3 | E18 | 72 | hr | 962 | 7568 | 10641 | 0.7112 | 0.8128 |
| MCF 10A | Palbociclib | 0.12 | uM | LJP6 | 1 | E17 | 72 | hr | 962 | 5931 | 10693 | 0.5546 | 0.6879 |
| MCF 10A | Palbociclib | 0.12 | uM | LJP6 | 2 | E17 | 72 | hr | 962 | 5793 | 10740 | 0.5394 | 0.6749 |
| MCF 10A | Palbociclib | 0.12 | uM | LJP6 | 3 | E17 | 72 | hr | 962 | 5887 | 10641 | 0.5532 | 0.6861 |