LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Erlotinib
10
uM
LJP5
 1
M19
 72
hr
 962 1443 10714 0.1347 0.1236
MCF 10A Erlotinib
10
uM
LJP5
 2
M19
 72
hr
 962 1597 10507 0.1520 0.1583
MCF 10A Erlotinib
10
uM
LJP5
 3
M19
 72
hr
 962 1465 10315 0.1420 0.1307
MCF 10A Gefitinib
0.04
uM
LJP6
 1
N12
 72
hr
 962 9014 10693 0.8429 0.9040
MCF 10A Gefitinib
0.04
uM
LJP6
 2
N12
 72
hr
 962 9264 10740 0.8625 0.9168
MCF 10A Gefitinib
0.04
uM
LJP6
 3
N12
 72
hr
 962 9310 10641 0.8749 0.9244
MCF 10A Gefitinib
0.12
uM
LJP6
 1
N11
 72
hr
 962 5273 10693 0.4931 0.6317
MCF 10A Gefitinib
0.12
uM
LJP6
 2
N11
 72
hr
 962 5296 10740 0.4931 0.6323
MCF 10A Gefitinib
0.12
uM
LJP6
 3
N11
 72
hr
 962 5095 10641 0.4788 0.6173
MCF 10A Gefitinib
0.37
uM
LJP6
 1
N10
 72
hr
 962 2185 10693 0.2043 0.2663
MCF 10A Gefitinib
0.37
uM
LJP6
 2
N10
 72
hr
 962 2434 10740 0.2266 0.3056
MCF 10A Gefitinib
0.37
uM
LJP6
 3
N10
 72
hr
 962 2183 10641 0.2051 0.2665
MCF 10A Gefitinib
1.11
uM
LJP6
 1
N09
 72
hr
 962 1442 10693 0.1349 0.1235
MCF 10A Gefitinib
1.11
uM
LJP6
 2
N09
 72
hr
 962 1522 10740 0.1417 0.1408
MCF 10A Gefitinib
1.11
uM
LJP6
 3
N09
 72
hr
 962 1446 10641 0.1359 0.1247
MCF 10A Gefitinib
3.33
uM
LJP6
 1
N08
 72
hr
 962 1355 10693 0.1267 0.1036
MCF 10A Gefitinib
3.33
uM
LJP6
 2
N08
 72
hr
 962 1467 10740 0.1366 0.1288
MCF 10A Gefitinib
3.33
uM
LJP6
 3
N08
 72
hr
 962 1384 10641 0.1301 0.1106
MCF 10A Gefitinib
10
uM
LJP6
 1
N07
 72
hr
 962 1261 10693 0.1179 0.0810
MCF 10A Gefitinib
10
uM
LJP6
 2
N07
 72
hr
 962 1109 10740 0.1033 0.0417
MCF 10A Gefitinib
10
uM
LJP6
 3
N07
 72
hr
 962 1418 10641 0.1333 0.1184
MCF 10A Nilotinib
0.04
uM
LJP5
 1
N18
 72
hr
 962 9835 10714 0.9180 0.9514
MCF 10A Nilotinib
0.04
uM
LJP5
 2
N18
 72
hr
 962 9886 10507 0.9408 0.9649
MCF 10A Nilotinib
0.04
uM
LJP5
 3
N18
 72
hr
 962 9624 10315 0.9330 0.9599
MCF 10A Nilotinib
0.12
uM
LJP5
 1
N17
 72
hr
 962 9718 10714 0.9070 0.9447