LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Nilotinib
0.12
uM
LJP5
 2
N17
 72
hr
 962 9967 10507 0.9485 0.9696
MCF 10A Nilotinib
0.12
uM
LJP5
 3
N17
 72
hr
 962 9266 10315 0.8983 0.9383
MCF 10A Nilotinib
0.37
uM
LJP5
 1
N16
 72
hr
 962 9935 10714 0.9273 0.9571
MCF 10A Nilotinib
0.37
uM
LJP5
 2
N16
 72
hr
 962 9625 10507 0.9160 0.9498
MCF 10A Nilotinib
0.37
uM
LJP5
 3
N16
 72
hr
 962 9149 10315 0.8869 0.9311
MCF 10A Nilotinib
1.11
uM
LJP5
 1
N15
 72
hr
 962 9572 10714 0.8934 0.9362
MCF 10A Nilotinib
1.11
uM
LJP5
 2
N15
 72
hr
 962 9575 10507 0.9112 0.9468
MCF 10A Nilotinib
1.11
uM
LJP5
 3
N15
 72
hr
 962 9326 10315 0.9041 0.9419
MCF 10A Nilotinib
3.33
uM
LJP5
 1
N14
 72
hr
 962 9297 10714 0.8677 0.9201
MCF 10A Nilotinib
3.33
uM
LJP5
 2
N14
 72
hr
 962 9812 10507 0.9338 0.9607
MCF 10A Nilotinib
3.33
uM
LJP5
 3
N14
 72
hr
 962 9369 10315 0.9083 0.9446
MCF 10A Nilotinib
10
uM
LJP5
 1
N13
 72
hr
 962 2358 10714 0.2201 0.2941
MCF 10A Nilotinib
10
uM
LJP5
 2
N13
 72
hr
 962 2949 10507 0.2807 0.3837
MCF 10A Nilotinib
10
uM
LJP5
 3
N13
 72
hr
 962 2849 10315 0.2762 0.3733
MCF 10A JNK-9L
0.04
uM
LJP6
 1
K24
 72
hr
 962 10992 10693 1.0279 1.0159
MCF 10A JNK-9L
0.04
uM
LJP6
 2
K24
 72
hr
 962 10923 10740 1.0170 1.0097
MCF 10A JNK-9L
0.04
uM
LJP6
 3
K24
 72
hr
 962 10639 10641 0.9998 0.9999
MCF 10A JNK-9L
0.12
uM
LJP6
 1
K23
 72
hr
 962 9889 10693 0.9248 0.9555
MCF 10A JNK-9L
0.12
uM
LJP6
 2
K23
 72
hr
 962 9859 10740 0.9179 0.9514
MCF 10A JNK-9L
0.12
uM
LJP6
 3
K23
 72
hr
 962 9717 10641 0.9131 0.9483
MCF 10A JNK-9L
0.37
uM
LJP6
 1
K22
 72
hr
 962 6252 10693 0.5847 0.7137
MCF 10A JNK-9L
0.37
uM
LJP6
 2
K22
 72
hr
 962 5799 10740 0.5399 0.6754
MCF 10A JNK-9L
0.37
uM
LJP6
 3
K22
 72
hr
 962 5683 10641 0.5340 0.6690
MCF 10A JNK-9L
1.11
uM
LJP6
 1
K21
 72
hr
 962 857 10693 0.0801 -0.0328
MCF 10A JNK-9L
1.11
uM
LJP6
 2
K21
 72
hr
 962 912 10740 0.0849 -0.0153