LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A NVP-AEW541
0.04
uM
LJP5
 3
E18
 72
hr
 962 10198 10315 0.9886 0.9933
MCF 10A NVP-AEW541
0.12
uM
LJP5
 1
E17
 72
hr
 962 10634 10714 0.9925 0.9957
MCF 10A NVP-AEW541
0.12
uM
LJP5
 2
E17
 72
hr
 962 10110 10507 0.9621 0.9777
MCF 10A NVP-AEW541
0.12
uM
LJP5
 3
E17
 72
hr
 962 10055 10315 0.9748 0.9851
MCF 10A NVP-AEW541
0.37
uM
LJP5
 1
E16
 72
hr
 962 10414 10714 0.9720 0.9837
MCF 10A NVP-AEW541
0.37
uM
LJP5
 2
E16
 72
hr
 962 9934 10507 0.9454 0.9677
MCF 10A NVP-AEW541
0.37
uM
LJP5
 3
E16
 72
hr
 962 9729 10315 0.9432 0.9661
MCF 10A NVP-AEW541
1.11
uM
LJP5
 1
E15
 72
hr
 962 9574 10714 0.8936 0.9363
MCF 10A NVP-AEW541
1.11
uM
LJP5
 2
E15
 72
hr
 962 9029 10507 0.8593 0.9140
MCF 10A NVP-AEW541
1.11
uM
LJP5
 3
E15
 72
hr
 962 9052 10315 0.8775 0.9251
MCF 10A NVP-AEW541
3.33
uM
LJP5
 1
E14
 72
hr
 962 9173 10714 0.8562 0.9126
MCF 10A NVP-AEW541
3.33
uM
LJP5
 2
E14
 72
hr
 962 8404 10507 0.7998 0.8746
MCF 10A NVP-AEW541
3.33
uM
LJP5
 3
E14
 72
hr
 962 8848 10315 0.8578 0.9123
MCF 10A NVP-AEW541
10
uM
LJP5
 1
E13
 72
hr
 962 5769 10714 0.5385 0.6738
MCF 10A NVP-AEW541
10
uM
LJP5
 2
E13
 72
hr
 962 5051 10507 0.4807 0.6173
MCF 10A NVP-AEW541
10
uM
LJP5
 3
E13
 72
hr
 962 5432 10315 0.5266 0.6582
MCF 10A PHA-665752
0.04
uM
LJP5
 1
F18
 72
hr
 962 10719 10714 1.0005 1.0003
MCF 10A PHA-665752
0.04
uM
LJP5
 2
F18
 72
hr
 962 10592 10507 1.0080 1.0046
MCF 10A PHA-665752
0.04
uM
LJP5
 3
F18
 72
hr
 962 10112 10315 0.9803 0.9884
MCF 10A PHA-665752
0.12
uM
LJP5
 1
F17
 72
hr
 962 10570 10714 0.9866 0.9922
MCF 10A PHA-665752
0.12
uM
LJP5
 2
F17
 72
hr
 962 10011 10507 0.9527 0.9721
MCF 10A PHA-665752
0.12
uM
LJP5
 3
F17
 72
hr
 962 9956 10315 0.9652 0.9794
MCF 10A PHA-665752
0.37
uM
LJP5
 1
F16
 72
hr
 962 10535 10714 0.9833 0.9903
MCF 10A PHA-665752
0.37
uM
LJP5
 2
F16
 72
hr
 962 9993 10507 0.9510 0.9711
MCF 10A PHA-665752
0.37
uM
LJP5
 3
F16
 72
hr
 962 9869 10315 0.9567 0.9743