LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Buparlisib
0.04
uM
LJP5
 1
H06
 72
hr
 962 10829 10714 1.0107 1.0062
MCF 10A Buparlisib
0.04
uM
LJP5
 2
H06
 72
hr
 962 11045 10507 1.0511 1.0291
MCF 10A Buparlisib
0.04
uM
LJP5
 3
H06
 72
hr
 962 10250 10315 0.9937 0.9963
MCF 10A Buparlisib
0.12
uM
LJP5
 1
H05
 72
hr
 962 10264 10714 0.9580 0.9755
MCF 10A Buparlisib
0.12
uM
LJP5
 2
H05
 72
hr
 962 10530 10507 1.0021 1.0012
MCF 10A Buparlisib
0.12
uM
LJP5
 3
H05
 72
hr
 962 9911 10315 0.9608 0.9768
MCF 10A Buparlisib
0.37
uM
LJP5
 1
H04
 72
hr
 962 9446 10714 0.8817 0.9288
MCF 10A Buparlisib
0.37
uM
LJP5
 2
H04
 72
hr
 962 9535 10507 0.9074 0.9445
MCF 10A Buparlisib
0.37
uM
LJP5
 3
H04
 72
hr
 962 9311 10315 0.9027 0.9410
MCF 10A Buparlisib
1.11
uM
LJP5
 1
H03
 72
hr
 962 6261 10714 0.5844 0.7137
MCF 10A Buparlisib
1.11
uM
LJP5
 2
H03
 72
hr
 962 6092 10507 0.5798 0.7076
MCF 10A Buparlisib
1.11
uM
LJP5
 3
H03
 72
hr
 962 5868 10315 0.5689 0.6961
MCF 10A Buparlisib
3.33
uM
LJP5
 1
H02
 72
hr
 962 1382 10714 0.1290 0.1098
MCF 10A Buparlisib
3.33
uM
LJP5
 2
H02
 72
hr
 962 1391 10507 0.1324 0.1128
MCF 10A Buparlisib
3.33
uM
LJP5
 3
H02
 72
hr
 962 1376 10315 0.1334 0.1102
MCF 10A Buparlisib
10
uM
LJP5
 1
H01
 72
hr
 962 546 10714 0.0510 -0.1504
MCF 10A Buparlisib
10
uM
LJP5
 2
H01
 72
hr
 962 672 10507 0.0640 -0.0988
MCF 10A Buparlisib
10
uM
LJP5
 3
H01
 72
hr
 962 540 10315 0.0524 -0.1553
MCF 10A XL147
0.04
uM
LJP5
 1
G12
 72
hr
 962 10899 10714 1.0173 1.0099
MCF 10A XL147
0.04
uM
LJP5
 2
G12
 72
hr
 962 10808 10507 1.0286 1.0164
MCF 10A XL147
0.04
uM
LJP5
 3
G12
 72
hr
 962 10505 10315 1.0184 1.0107
MCF 10A XL147
0.12
uM
LJP5
 1
G11
 72
hr
 962 10275 10714 0.9590 0.9761
MCF 10A XL147
0.12
uM
LJP5
 2
G11
 72
hr
 962 9888 10507 0.9410 0.9651
MCF 10A XL147
0.12
uM
LJP5
 3
G11
 72
hr
 962 9935 10315 0.9631 0.9782
MCF 10A XL147
0.37
uM
LJP5
 1
G10
 72
hr
 962 9848 10714 0.9192 0.9521