LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | CHIR-99021 | 10 | uM | LJP6 | 2 | P13 | 72 | hr | 962 | 9245 | 10740 | 0.8607 | 0.9157 |
| MCF 10A | CHIR-99021 | 10 | uM | LJP6 | 3 | P13 | 72 | hr | 962 | 8062 | 10641 | 0.7576 | 0.8461 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 1 | J12 | 72 | hr | 962 | 11272 | 10693 | 1.0541 | 1.0306 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 2 | J12 | 72 | hr | 962 | 11392 | 10740 | 1.0606 | 1.0341 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 3 | J12 | 72 | hr | 962 | 11577 | 10641 | 1.0879 | 1.0492 |
| MCF 10A | Linifanib | 0.12 | uM | LJP6 | 1 | J11 | 72 | hr | 962 | 11263 | 10693 | 1.0532 | 1.0301 |
| MCF 10A | Linifanib | 0.12 | uM | LJP6 | 2 | J11 | 72 | hr | 962 | 11288 | 10740 | 1.0509 | 1.0288 |
| MCF 10A | Linifanib | 0.12 | uM | LJP6 | 3 | J11 | 72 | hr | 962 | 11307 | 10641 | 1.0625 | 1.0353 |
| MCF 10A | Linifanib | 0.37 | uM | LJP6 | 1 | J10 | 72 | hr | 962 | 11406 | 10693 | 1.0666 | 1.0375 |
| MCF 10A | Linifanib | 0.37 | uM | LJP6 | 2 | J10 | 72 | hr | 962 | 11555 | 10740 | 1.0758 | 1.0424 |
| MCF 10A | Linifanib | 0.37 | uM | LJP6 | 3 | J10 | 72 | hr | 962 | 11261 | 10641 | 1.0582 | 1.0329 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 1 | J09 | 72 | hr | 962 | 11323 | 10693 | 1.0589 | 1.0332 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 2 | J09 | 72 | hr | 962 | 11431 | 10740 | 1.0643 | 1.0361 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 3 | J09 | 72 | hr | 962 | 11496 | 10641 | 1.0803 | 1.0450 |
| MCF 10A | Linifanib | 3.33 | uM | LJP6 | 1 | J08 | 72 | hr | 962 | 11201 | 10693 | 1.0474 | 1.0269 |
| MCF 10A | Linifanib | 3.33 | uM | LJP6 | 2 | J08 | 72 | hr | 962 | 11395 | 10740 | 1.0609 | 1.0343 |
| MCF 10A | Linifanib | 3.33 | uM | LJP6 | 3 | J08 | 72 | hr | 962 | 10886 | 10641 | 1.0230 | 1.0131 |
| MCF 10A | Linifanib | 10 | uM | LJP6 | 1 | J07 | 72 | hr | 962 | 7927 | 10693 | 0.7413 | 0.8349 |
| MCF 10A | Linifanib | 10 | uM | LJP6 | 2 | J07 | 72 | hr | 962 | 7737 | 10740 | 0.7203 | 0.8201 |
| MCF 10A | Linifanib | 10 | uM | LJP6 | 3 | J07 | 72 | hr | 962 | 8092 | 10641 | 0.7604 | 0.8481 |
| MCF 10A | PIK-93 | 0.04 | uM | LJP5 | 1 | K18 | 72 | hr | 962 | 10534 | 10714 | 0.9832 | 0.9903 |
| MCF 10A | PIK-93 | 0.04 | uM | LJP5 | 2 | K18 | 72 | hr | 962 | 10491 | 10507 | 0.9984 | 0.9991 |
| MCF 10A | PIK-93 | 0.04 | uM | LJP5 | 3 | K18 | 72 | hr | 962 | 10062 | 10315 | 0.9755 | 0.9855 |
| MCF 10A | PIK-93 | 0.12 | uM | LJP5 | 1 | K17 | 72 | hr | 962 | 10201 | 10714 | 0.9521 | 0.9720 |
| MCF 10A | PIK-93 | 0.12 | uM | LJP5 | 2 | K17 | 72 | hr | 962 | 10452 | 10507 | 0.9947 | 0.9969 |