LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A PIK-93
0.12
uM
LJP5
 3
K17
 72
hr
 962 9454 10315 0.9165 0.9497
MCF 10A PIK-93
0.37
uM
LJP5
 1
K16
 72
hr
 962 9633 10714 0.8991 0.9398
MCF 10A PIK-93
0.37
uM
LJP5
 2
K16
 72
hr
 962 10248 10507 0.9753 0.9855
MCF 10A PIK-93
0.37
uM
LJP5
 3
K16
 72
hr
 962 9590 10315 0.9297 0.9579
MCF 10A PIK-93
1.11
uM
LJP5
 1
K15
 72
hr
 962 9264 10714 0.8647 0.9181
MCF 10A PIK-93
1.11
uM
LJP5
 2
K15
 72
hr
 962 9853 10507 0.9377 0.9630
MCF 10A PIK-93
1.11
uM
LJP5
 3
K15
 72
hr
 962 8914 10315 0.8642 0.9165
MCF 10A PIK-93
3.33
uM
LJP5
 1
K14
 72
hr
 962 8489 10714 0.7923 0.8705
MCF 10A PIK-93
3.33
uM
LJP5
 2
K14
 72
hr
 962 9191 10507 0.8747 0.9238
MCF 10A PIK-93
3.33
uM
LJP5
 3
K14
 72
hr
 962 8020 10315 0.7775 0.8582
MCF 10A PIK-93
10
uM
LJP5
 1
K13
 72
hr
 962 4747 10714 0.4431 0.5825
MCF 10A PIK-93
10
uM
LJP5
 2
K13
 72
hr
 962 3901 10507 0.3713 0.5006
MCF 10A PIK-93
10
uM
LJP5
 3
K13
 72
hr
 962 4544 10315 0.4405 0.5740
MCF 10A Dactolisib
0.04
uM
LJP5
 1
M18
 72
hr
 962 1600 10714 0.1493 0.1575
MCF 10A Dactolisib
0.04
uM
LJP5
 2
M18
 72
hr
 962 1698 10507 0.1616 0.1790
MCF 10A Dactolisib
0.04
uM
LJP5
 3
M18
 72
hr
 962 1577 10315 0.1529 0.1553
MCF 10A Dactolisib
0.12
uM
LJP5
 1
M17
 72
hr
 962 1610 10714 0.1503 0.1596
MCF 10A Dactolisib
0.12
uM
LJP5
 2
M17
 72
hr
 962 1654 10507 0.1574 0.1701
MCF 10A Dactolisib
0.12
uM
LJP5
 3
M17
 72
hr
 962 1348 10315 0.1307 0.1035
MCF 10A Dactolisib
0.37
uM
LJP5
 1
M16
 72
hr
 962 1549 10714 0.1446 0.1468
MCF 10A Dactolisib
0.37
uM
LJP5
 2
M16
 72
hr
 962 1670 10507 0.1589 0.1734
MCF 10A Dactolisib
0.37
uM
LJP5
 3
M16
 72
hr
 962 1450 10315 0.1406 0.1273
MCF 10A Dactolisib
1.11
uM
LJP5
 1
M15
 72
hr
 962 1402 10714 0.1309 0.1144
MCF 10A Dactolisib
1.11
uM
LJP5
 2
M15
 72
hr
 962 1398 10507 0.1330 0.1144
MCF 10A Dactolisib
1.11
uM
LJP5
 3
M15
 72
hr
 962 1427 10315 0.1383 0.1221