LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Trametinib
1.11
uM
LJP5
 3
P21
 72
hr
 962 1960 10315 0.1900 0.2311
MCF 10A Trametinib
3.33
uM
LJP5
 1
P20
 72
hr
 962 1720 10714 0.1605 0.1818
MCF 10A Trametinib
3.33
uM
LJP5
 2
P20
 72
hr
 962 1990 10507 0.1894 0.2345
MCF 10A Trametinib
3.33
uM
LJP5
 3
P20
 72
hr
 962 2065 10315 0.2002 0.2500
MCF 10A Trametinib
10
uM
LJP5
 1
P19
 72
hr
 962 1932 10714 0.1803 0.2220
MCF 10A Trametinib
10
uM
LJP5
 2
P19
 72
hr
 962 1951 10507 0.1857 0.2275
MCF 10A Trametinib
10
uM
LJP5
 3
P19
 72
hr
 962 2055 10315 0.1992 0.2482
MCF 10A Omipalisib
0.04
uM
LJP6
 1
N06
 72
hr
 962 934 10693 0.0873 -0.0085
MCF 10A Omipalisib
0.04
uM
LJP6
 2
N06
 72
hr
 962 1014 10740 0.0944 0.0152
MCF 10A Omipalisib
0.04
uM
LJP6
 3
N06
 72
hr
 962 1079 10641 0.1014 0.0336
MCF 10A Omipalisib
0.12
uM
LJP6
 1
N05
 72
hr
 962 888 10693 0.0830 -0.0228
MCF 10A Omipalisib
0.12
uM
LJP6
 2
N05
 72
hr
 962 788 10740 0.0734 -0.0558
MCF 10A Omipalisib
0.12
uM
LJP6
 3
N05
 72
hr
 962 883 10641 0.0830 -0.0245
MCF 10A Omipalisib
0.37
uM
LJP6
 1
N04
 72
hr
 962 816 10693 0.0763 -0.0463
MCF 10A Omipalisib
0.37
uM
LJP6
 2
N04
 72
hr
 962 871 10740 0.0811 -0.0282
MCF 10A Omipalisib
0.37
uM
LJP6
 3
N04
 72
hr
 962 1010 10641 0.0949 0.0141
MCF 10A Omipalisib
1.11
uM
LJP6
 1
N03
 72
hr
 962 858 10693 0.0802 -0.0324
MCF 10A Omipalisib
1.11
uM
LJP6
 2
N03
 72
hr
 962 870 10740 0.0810 -0.0285
MCF 10A Omipalisib
1.11
uM
LJP6
 3
N03
 72
hr
 962 889 10641 0.0835 -0.0226
MCF 10A Omipalisib
3.33
uM
LJP6
 1
N02
 72
hr
 962 705 10693 0.0659 -0.0856
MCF 10A Omipalisib
3.33
uM
LJP6
 2
N02
 72
hr
 962 765 10740 0.0712 -0.0638
MCF 10A Omipalisib
3.33
uM
LJP6
 3
N02
 72
hr
 962 786 10641 0.0739 -0.0567
MCF 10A Omipalisib
10
uM
LJP6
 1
N01
 72
hr
 962 683 10693 0.0639 -0.0939
MCF 10A Omipalisib
10
uM
LJP6
 2
N01
 72
hr
 962 714 10740 0.0665 -0.0821
MCF 10A Omipalisib
10
uM
LJP6
 3
N01
 72
hr
 962 765 10641 0.0719 -0.0640