LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A JNK-9L
1.11
uM
LJP6
 3
K21
 72
hr
 962 1010 10641 0.0949 0.0141
MCF 10A JNK-9L
3.33
uM
LJP6
 1
K20
 72
hr
 962 387 10693 0.0362 -0.2306
MCF 10A JNK-9L
3.33
uM
LJP6
 2
K20
 72
hr
 962 449 10740 0.0418 -0.1967
MCF 10A JNK-9L
3.33
uM
LJP6
 3
K20
 72
hr
 962 545 10641 0.0512 -0.1512
MCF 10A JNK-9L
10
uM
LJP6
 1
K19
 72
hr
 962 729 10693 0.0682 -0.0768
MCF 10A JNK-9L
10
uM
LJP6
 2
K19
 72
hr
 962 632 10740 0.0588 -0.1137
MCF 10A JNK-9L
10
uM
LJP6
 3
K19
 72
hr
 962 806 10641 0.0757 -0.0498
MCF 10A PD0325901
0.04
uM
LJP6
 1
E06
 72
hr
 962 2083 10693 0.1948 0.2490
MCF 10A PD0325901
0.04
uM
LJP6
 2
E06
 72
hr
 962 2080 10740 0.1937 0.2479
MCF 10A PD0325901
0.04
uM
LJP6
 3
E06
 72
hr
 962 2474 10641 0.2325 0.3131
MCF 10A PD0325901
0.04
uM
LJP5
 1
C06
 72
hr
 962 2960 10714 0.2763 0.3815
MCF 10A PD0325901
0.04
uM
LJP5
 2
C06
 72
hr
 962 2126 10507 0.2023 0.2584
MCF 10A PD0325901
0.04
uM
LJP5
 3
C06
 72
hr
 962 2716 10315 0.2633 0.3542
MCF 10A PD0325901
0.12
uM
LJP6
 1
E05
 72
hr
 962 1838 10693 0.1719 0.2048
MCF 10A PD0325901
0.12
uM
LJP6
 2
E05
 72
hr
 962 1924 10740 0.1791 0.2203
MCF 10A PD0325901
0.12
uM
LJP6
 3
E05
 72
hr
 962 1890 10641 0.1776 0.2150
MCF 10A PD0325901
0.12
uM
LJP5
 1
C05
 72
hr
 962 2064 10714 0.1927 0.2455
MCF 10A PD0325901
0.12
uM
LJP5
 2
C05
 72
hr
 962 1901 10507 0.1809 0.2183
MCF 10A PD0325901
0.12
uM
LJP5
 3
C05
 72
hr
 962 1820 10315 0.1764 0.2047
MCF 10A PD0325901
0.37
uM
LJP6
 1
E04
 72
hr
 962 1559 10693 0.1458 0.1490
MCF 10A PD0325901
0.37
uM
LJP6
 2
E04
 72
hr
 962 1812 10740 0.1687 0.1995
MCF 10A PD0325901
0.37
uM
LJP6
 3
E04
 72
hr
 962 1752 10641 0.1646 0.1887
MCF 10A PD0325901
0.37
uM
LJP5
 1
C04
 72
hr
 962 1881 10714 0.1756 0.2126
MCF 10A PD0325901
0.37
uM
LJP5
 2
C04
 72
hr
 962 1746 10507 0.1662 0.1886
MCF 10A PD0325901
0.37
uM
LJP5
 3
C04
 72
hr
 962 1853 10315 0.1796 0.2111