LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A PF562271
3.33
uM
LJP6
 2
F14
 72
hr
 962 1154 10740 0.1074 0.0536
MCF 10A PF562271
3.33
uM
LJP6
 3
F14
 72
hr
 962 1399 10641 0.1315 0.1140
MCF 10A PF562271
10
uM
LJP6
 1
F13
 72
hr
 962 345 10693 0.0323 -0.2556
MCF 10A PF562271
10
uM
LJP6
 2
F13
 72
hr
 962 398 10740 0.0371 -0.2240
MCF 10A PF562271
10
uM
LJP6
 3
F13
 72
hr
 962 365 10641 0.0343 -0.2439
MCF 10A PHA-793887
0.04
uM
LJP6
 1
E24
 72
hr
 962 3055 10693 0.2857 0.3945
MCF 10A PHA-793887
0.04
uM
LJP6
 2
E24
 72
hr
 962 3085 10740 0.2872 0.3976
MCF 10A PHA-793887
0.04
uM
LJP6
 3
E24
 72
hr
 962 3130 10641 0.2941 0.4052
MCF 10A PHA-793887
0.12
uM
LJP6
 1
E23
 72
hr
 962 1773 10693 0.1658 0.1924
MCF 10A PHA-793887
0.12
uM
LJP6
 2
E23
 72
hr
 962 1834 10740 0.1708 0.2036
MCF 10A PHA-793887
0.12
uM
LJP6
 3
E23
 72
hr
 962 1970 10641 0.1851 0.2296
MCF 10A PHA-793887
0.37
uM
LJP6
 1
E22
 72
hr
 962 1193 10693 0.1116 0.0639
MCF 10A PHA-793887
0.37
uM
LJP6
 2
E22
 72
hr
 962 1164 10740 0.1084 0.0562
MCF 10A PHA-793887
0.37
uM
LJP6
 3
E22
 72
hr
 962 1315 10641 0.1236 0.0943
MCF 10A PHA-793887
1.11
uM
LJP6
 1
E21
 72
hr
 962 829 10693 0.0775 -0.0420
MCF 10A PHA-793887
1.11
uM
LJP6
 2
E21
 72
hr
 962 871 10740 0.0811 -0.0282
MCF 10A PHA-793887
1.11
uM
LJP6
 3
E21
 72
hr
 962 843 10641 0.0792 -0.0374
MCF 10A PHA-793887
3.33
uM
LJP6
 1
E20
 72
hr
 962 573 10693 0.0536 -0.1386
MCF 10A PHA-793887
3.33
uM
LJP6
 2
E20
 72
hr
 962 585 10740 0.0545 -0.1332
MCF 10A PHA-793887
3.33
uM
LJP6
 3
E20
 72
hr
 962 654 10641 0.0615 -0.1054
MCF 10A PHA-793887
10
uM
LJP6
 1
E19
 72
hr
 962 289 10693 0.0270 -0.2926
MCF 10A PHA-793887
10
uM
LJP6
 2
E19
 72
hr
 962 449 10740 0.0418 -0.1967
MCF 10A PHA-793887
10
uM
LJP6
 3
E19
 72
hr
 962 341 10641 0.0320 -0.2586
MCF 10A QL-X-138
0.04
uM
LJP6
 1
F24
 72
hr
 962 11008 10693 1.0294 1.0167
MCF 10A QL-X-138
0.04
uM
LJP6
 2
F24
 72
hr
 962 11090 10740 1.0325 1.0185