LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Lapatinib
10
uM
LJP6
 1
M19
 72
hr
 962 2544 10693 0.2379 0.3229
MCF 10A Lapatinib
10
uM
LJP6
 2
M19
 72
hr
 962 3074 10740 0.2862 0.3961
MCF 10A Lapatinib
10
uM
LJP6
 3
M19
 72
hr
 962 2361 10641 0.2219 0.2955
MCF 10A Sirolimus
0.04
uM
LJP6
 1
L18
 72
hr
 962 9388 10693 0.8779 0.9264
MCF 10A Sirolimus
0.04
uM
LJP6
 2
L18
 72
hr
 962 9559 10740 0.8900 0.9341
MCF 10A Sirolimus
0.04
uM
LJP6
 3
L18
 72
hr
 962 9098 10641 0.8549 0.9116
MCF 10A Sirolimus
0.12
uM
LJP6
 1
L17
 72
hr
 962 9685 10693 0.9057 0.9438
MCF 10A Sirolimus
0.12
uM
LJP6
 2
L17
 72
hr
 962 9580 10740 0.8919 0.9354
MCF 10A Sirolimus
0.12
uM
LJP6
 3
L17
 72
hr
 962 9318 10641 0.8756 0.9248
MCF 10A Sirolimus
0.37
uM
LJP6
 1
L16
 72
hr
 962 9201 10693 0.8604 0.9153
MCF 10A Sirolimus
0.37
uM
LJP6
 2
L16
 72
hr
 962 9615 10740 0.8952 0.9374
MCF 10A Sirolimus
0.37
uM
LJP6
 3
L16
 72
hr
 962 9063 10641 0.8517 0.9095
MCF 10A Sirolimus
1.11
uM
LJP6
 1
L15
 72
hr
 962 9559 10693 0.8939 0.9365
MCF 10A Sirolimus
1.11
uM
LJP6
 2
L15
 72
hr
 962 9507 10740 0.8851 0.9311
MCF 10A Sirolimus
1.11
uM
LJP6
 3
L15
 72
hr
 962 9207 10641 0.8652 0.9182
MCF 10A Sirolimus
3.33
uM
LJP6
 1
L14
 72
hr
 962 8965 10693 0.8384 0.9010
MCF 10A Sirolimus
3.33
uM
LJP6
 2
L14
 72
hr
 962 9580 10740 0.8919 0.9354
MCF 10A Sirolimus
3.33
uM
LJP6
 3
L14
 72
hr
 962 9057 10641 0.8511 0.9091
MCF 10A Sirolimus
10
uM
LJP6
 1
L13
 72
hr
 962 9199 10693 0.8602 0.9152
MCF 10A Sirolimus
10
uM
LJP6
 2
L13
 72
hr
 962 9265 10740 0.8626 0.9169
MCF 10A Sirolimus
10
uM
LJP6
 3
L13
 72
hr
 962 8631 10641 0.8111 0.8828
MCF 10A ZSTK474
0.04
uM
LJP6
 1
M18
 72
hr
 962 10832 10693 1.0129 1.0074
MCF 10A ZSTK474
0.04
uM
LJP6
 2
M18
 72
hr
 962 11033 10740 1.0272 1.0155
MCF 10A ZSTK474
0.04
uM
LJP6
 3
M18
 72
hr
 962 10201 10641 0.9586 0.9758
MCF 10A ZSTK474
0.12
uM
LJP6
 1
M17
 72
hr
 962 9524 10693 0.8906 0.9344