LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A PLX-4720
0.37
uM
LJP5
 3
K04
 72
hr
 962 8864 10315 0.8593 0.9133
MCF 10A PLX-4720
1.11
uM
LJP5
 1
K03
 72
hr
 962 9123 10714 0.8515 0.9096
MCF 10A PLX-4720
1.11
uM
LJP5
 2
K03
 72
hr
 962 9513 10507 0.9053 0.9432
MCF 10A PLX-4720
1.11
uM
LJP5
 3
K03
 72
hr
 962 8968 10315 0.8694 0.9199
MCF 10A PLX-4720
3.33
uM
LJP5
 1
K02
 72
hr
 962 9182 10714 0.8570 0.9132
MCF 10A PLX-4720
3.33
uM
LJP5
 2
K02
 72
hr
 962 9664 10507 0.9197 0.9520
MCF 10A PLX-4720
3.33
uM
LJP5
 3
K02
 72
hr
 962 9091 10315 0.8813 0.9275
MCF 10A PLX-4720
10
uM
LJP5
 1
K01
 72
hr
 962 8662 10714 0.8085 0.8814
MCF 10A PLX-4720
10
uM
LJP5
 2
K01
 72
hr
 962 9212 10507 0.8767 0.9251
MCF 10A PLX-4720
10
uM
LJP5
 3
K01
 72
hr
 962 8954 10315 0.8680 0.9190
MCF 10A Lapatinib
0.04
uM
LJP6
 1
M24
 72
hr
 962 10732 10693 1.0036 1.0021
MCF 10A Lapatinib
0.04
uM
LJP6
 2
M24
 72
hr
 962 10865 10740 1.0116 1.0066
MCF 10A Lapatinib
0.04
uM
LJP6
 3
M24
 72
hr
 962 10646 10641 1.0004 1.0002
MCF 10A Lapatinib
0.12
uM
LJP6
 1
M23
 72
hr
 962 10638 10693 0.9948 0.9970
MCF 10A Lapatinib
0.12
uM
LJP6
 2
M23
 72
hr
 962 10589 10740 0.9859 0.9918
MCF 10A Lapatinib
0.12
uM
LJP6
 3
M23
 72
hr
 962 10513 10641 0.9879 0.9930
MCF 10A Lapatinib
0.37
uM
LJP6
 1
M22
 72
hr
 962 10549 10693 0.9865 0.9922
MCF 10A Lapatinib
0.37
uM
LJP6
 2
M22
 72
hr
 962 10585 10740 0.9855 0.9916
MCF 10A Lapatinib
0.37
uM
LJP6
 3
M22
 72
hr
 962 10713 10641 1.0067 1.0039
MCF 10A Lapatinib
1.11
uM
LJP6
 1
M21
 72
hr
 962 10136 10693 0.9479 0.9694
MCF 10A Lapatinib
1.11
uM
LJP6
 2
M21
 72
hr
 962 10079 10740 0.9384 0.9638
MCF 10A Lapatinib
1.11
uM
LJP6
 3
M21
 72
hr
 962 10360 10641 0.9735 0.9846
MCF 10A Lapatinib
3.33
uM
LJP6
 1
M20
 72
hr
 962 8494 10693 0.7943 0.8717
MCF 10A Lapatinib
3.33
uM
LJP6
 2
M20
 72
hr
 962 8532 10740 0.7944 0.8720
MCF 10A Lapatinib
3.33
uM
LJP6
 3
M20
 72
hr
 962 8724 10641 0.8198 0.8886