LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A PD173074
10
uM
LJP6
 3
I07
 72
hr
 962 7221 10641 0.6786 0.7884
MCF 10A Crizotinib
0.04
uM
LJP5
 1
A24
 72
hr
 962 10613 10714 0.9906 0.9946
MCF 10A Crizotinib
0.04
uM
LJP5
 2
A24
 72
hr
 962 10906 10507 1.0379 1.0217
MCF 10A Crizotinib
0.04
uM
LJP5
 3
A24
 72
hr
 962 10582 10315 1.0259 1.0150
MCF 10A Crizotinib
0.12
uM
LJP5
 1
A23
 72
hr
 962 10487 10714 0.9788 0.9877
MCF 10A Crizotinib
0.12
uM
LJP5
 2
A23
 72
hr
 962 10635 10507 1.0121 1.0070
MCF 10A Crizotinib
0.12
uM
LJP5
 3
A23
 72
hr
 962 10184 10315 0.9873 0.9925
MCF 10A Crizotinib
0.37
uM
LJP5
 1
A22
 72
hr
 962 9849 10714 0.9193 0.9522
MCF 10A Crizotinib
0.37
uM
LJP5
 2
A22
 72
hr
 962 9965 10507 0.9483 0.9695
MCF 10A Crizotinib
0.37
uM
LJP5
 3
A22
 72
hr
 962 9555 10315 0.9263 0.9558
MCF 10A Crizotinib
1.11
uM
LJP5
 1
A21
 72
hr
 962 9111 10714 0.8504 0.9089
MCF 10A Crizotinib
1.11
uM
LJP5
 2
A21
 72
hr
 962 9313 10507 0.8863 0.9312
MCF 10A Crizotinib
1.11
uM
LJP5
 3
A21
 72
hr
 962 8866 10315 0.8595 0.9135
MCF 10A Crizotinib
3.33
uM
LJP5
 1
A20
 72
hr
 962 7943 10714 0.7414 0.8351
MCF 10A Crizotinib
3.33
uM
LJP5
 2
A20
 72
hr
 962 8298 10507 0.7897 0.8677
MCF 10A Crizotinib
3.33
uM
LJP5
 3
A20
 72
hr
 962 7704 10315 0.7469 0.8365
MCF 10A Crizotinib
10
uM
LJP5
 1
A19
 72
hr
 962 1318 10714 0.1230 0.0947
MCF 10A Crizotinib
10
uM
LJP5
 2
A19
 72
hr
 962 1421 10507 0.1352 0.1197
MCF 10A Crizotinib
10
uM
LJP5
 3
A19
 72
hr
 962 1438 10315 0.1394 0.1246
MCF 10A BMS345541
0.04
uM
LJP6
 1
D06
 72
hr
 962 10559 10693 0.9874 0.9927
MCF 10A BMS345541
0.04
uM
LJP6
 2
D06
 72
hr
 962 10605 10740 0.9874 0.9927
MCF 10A BMS345541
0.04
uM
LJP6
 3
D06
 72
hr
 962 10272 10641 0.9653 0.9797
MCF 10A BMS345541
0.12
uM
LJP6
 1
D05
 72
hr
 962 10458 10693 0.9780 0.9872
MCF 10A BMS345541
0.12
uM
LJP6
 2
D05
 72
hr
 962 10386 10740 0.9670 0.9808
MCF 10A BMS345541
0.12
uM
LJP6
 3
D05
 72
hr
 962 9827 10641 0.9235 0.9546