LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A ZSTK474
0.12
uM
LJP6
 2
M17
 72
hr
 962 9259 10740 0.8620 0.9165
MCF 10A ZSTK474
0.12
uM
LJP6
 3
M17
 72
hr
 962 8568 10641 0.8051 0.8788
MCF 10A ZSTK474
0.37
uM
LJP6
 1
M16
 72
hr
 962 7810 10693 0.7303 0.8270
MCF 10A ZSTK474
0.37
uM
LJP6
 2
M16
 72
hr
 962 7322 10740 0.6817 0.7915
MCF 10A ZSTK474
0.37
uM
LJP6
 3
M16
 72
hr
 962 6853 10641 0.6440 0.7616
MCF 10A ZSTK474
1.11
uM
LJP6
 1
M15
 72
hr
 962 3833 10693 0.3584 0.4886
MCF 10A ZSTK474
1.11
uM
LJP6
 2
M15
 72
hr
 962 3927 10740 0.3656 0.4979
MCF 10A ZSTK474
1.11
uM
LJP6
 3
M15
 72
hr
 962 3547 10641 0.3333 0.4569
MCF 10A ZSTK474
3.33
uM
LJP6
 1
M14
 72
hr
 962 2261 10693 0.2114 0.2788
MCF 10A ZSTK474
3.33
uM
LJP6
 2
M14
 72
hr
 962 2213 10740 0.2060 0.2704
MCF 10A ZSTK474
3.33
uM
LJP6
 3
M14
 72
hr
 962 2164 10641 0.2034 0.2634
MCF 10A ZSTK474
10
uM
LJP6
 1
M13
 72
hr
 962 1396 10693 0.1305 0.1131
MCF 10A ZSTK474
10
uM
LJP6
 2
M13
 72
hr
 962 1261 10740 0.1174 0.0808
MCF 10A ZSTK474
10
uM
LJP6
 3
M13
 72
hr
 962 1392 10641 0.1308 0.1124
MCF 10A BX-912
0.04
uM
LJP5
 1
L24
 72
hr
 962 9923 10714 0.9262 0.9564
MCF 10A BX-912
0.04
uM
LJP5
 2
L24
 72
hr
 962 9653 10507 0.9187 0.9514
MCF 10A BX-912
0.04
uM
LJP5
 3
L24
 72
hr
 962 9411 10315 0.9123 0.9471
MCF 10A BX-912
0.12
uM
LJP5
 1
L23
 72
hr
 962 8139 10714 0.7597 0.8480
MCF 10A BX-912
0.12
uM
LJP5
 2
L23
 72
hr
 962 8183 10507 0.7788 0.8601
MCF 10A BX-912
0.12
uM
LJP5
 3
L23
 72
hr
 962 7726 10315 0.7490 0.8380
MCF 10A BX-912
0.37
uM
LJP5
 1
L22
 72
hr
 962 2226 10714 0.2078 0.2728
MCF 10A BX-912
0.37
uM
LJP5
 2
L22
 72
hr
 962 2364 10507 0.2250 0.2978
MCF 10A BX-912
0.37
uM
LJP5
 3
L22
 72
hr
 962 2572 10315 0.2493 0.3328
MCF 10A BX-912
1.11
uM
LJP5
 1
L21
 72
hr
 962 1591 10714 0.1485 0.1556
MCF 10A BX-912
1.11
uM
LJP5
 2
L21
 72
hr
 962 1633 10507 0.1554 0.1658