LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A XMD16-144
0.37
uM
LJP5
 3
M10
 72
hr
 962 1596 10315 0.1547 0.1594
MCF 10A XMD16-144
1.11
uM
LJP5
 1
M09
 72
hr
 962 1387 10714 0.1295 0.1109
MCF 10A XMD16-144
1.11
uM
LJP5
 2
M09
 72
hr
 962 1458 10507 0.1388 0.1281
MCF 10A XMD16-144
1.11
uM
LJP5
 3
M09
 72
hr
 962 1470 10315 0.1425 0.1318
MCF 10A XMD16-144
3.33
uM
LJP5
 1
M08
 72
hr
 962 1256 10714 0.1172 0.0797
MCF 10A XMD16-144
3.33
uM
LJP5
 2
M08
 72
hr
 962 1341 10507 0.1276 0.1010
MCF 10A XMD16-144
3.33
uM
LJP5
 3
M08
 72
hr
 962 1199 10315 0.1162 0.0664
MCF 10A XMD16-144
10
uM
LJP5
 1
M07
 72
hr
 962 922 10714 0.0861 -0.0122
MCF 10A XMD16-144
10
uM
LJP5
 2
M07
 72
hr
 962 1131 10507 0.1076 0.0480
MCF 10A XMD16-144
10
uM
LJP5
 3
M07
 72
hr
 962 886 10315 0.0859 -0.0238
MCF 10A Erlotinib
0.04
uM
LJP5
 1
M24
 72
hr
 962 9800 10714 0.9147 0.9494
MCF 10A Erlotinib
0.04
uM
LJP5
 2
M24
 72
hr
 962 9892 10507 0.9414 0.9653
MCF 10A Erlotinib
0.04
uM
LJP5
 3
M24
 72
hr
 962 9609 10315 0.9315 0.9590
MCF 10A Erlotinib
0.12
uM
LJP5
 1
M23
 72
hr
 962 5472 10714 0.5107 0.6486
MCF 10A Erlotinib
0.12
uM
LJP5
 2
M23
 72
hr
 962 5791 10507 0.5511 0.6827
MCF 10A Erlotinib
0.12
uM
LJP5
 3
M23
 72
hr
 962 5629 10315 0.5457 0.6756
MCF 10A Erlotinib
0.37
uM
LJP5
 1
M22
 72
hr
 962 2106 10714 0.1966 0.2527
MCF 10A Erlotinib
0.37
uM
LJP5
 2
M22
 72
hr
 962 2269 10507 0.2159 0.2824
MCF 10A Erlotinib
0.37
uM
LJP5
 3
M22
 72
hr
 962 2265 10315 0.2196 0.2842
MCF 10A Erlotinib
1.11
uM
LJP5
 1
M21
 72
hr
 962 1387 10714 0.1295 0.1109
MCF 10A Erlotinib
1.11
uM
LJP5
 2
M21
 72
hr
 962 1534 10507 0.1460 0.1448
MCF 10A Erlotinib
1.11
uM
LJP5
 3
M21
 72
hr
 962 1460 10315 0.1415 0.1296
MCF 10A Erlotinib
3.33
uM
LJP5
 1
M20
 72
hr
 962 1523 10714 0.1422 0.1412
MCF 10A Erlotinib
3.33
uM
LJP5
 2
M20
 72
hr
 962 1638 10507 0.1559 0.1668
MCF 10A Erlotinib
3.33
uM
LJP5
 3
M20
 72
hr
 962 1443 10315 0.1399 0.1257