LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A WYE-125132
0.12
uM
LJP6
 1
L11
 72
hr
 962 1930 10693 0.1805 0.2218
MCF 10A WYE-125132
0.12
uM
LJP6
 2
L11
 72
hr
 962 1968 10740 0.1832 0.2283
MCF 10A WYE-125132
0.12
uM
LJP6
 3
L11
 72
hr
 962 1944 10641 0.1827 0.2249
MCF 10A WYE-125132
0.37
uM
LJP6
 1
L10
 72
hr
 962 1524 10693 0.1425 0.1415
MCF 10A WYE-125132
0.37
uM
LJP6
 2
L10
 72
hr
 962 1760 10740 0.1639 0.1895
MCF 10A WYE-125132
0.37
uM
LJP6
 3
L10
 72
hr
 962 1577 10641 0.1482 0.1532
MCF 10A WYE-125132
1.11
uM
LJP6
 1
L09
 72
hr
 962 1560 10693 0.1459 0.1492
MCF 10A WYE-125132
1.11
uM
LJP6
 2
L09
 72
hr
 962 1589 10740 0.1479 0.1550
MCF 10A WYE-125132
1.11
uM
LJP6
 3
L09
 72
hr
 962 1674 10641 0.1573 0.1732
MCF 10A WYE-125132
3.33
uM
LJP6
 1
L08
 72
hr
 962 1416 10693 0.1324 0.1176
MCF 10A WYE-125132
3.33
uM
LJP6
 2
L08
 72
hr
 962 1396 10740 0.1300 0.1129
MCF 10A WYE-125132
3.33
uM
LJP6
 3
L08
 72
hr
 962 1439 10641 0.1352 0.1231
MCF 10A WYE-125132
10
uM
LJP6
 1
L07
 72
hr
 962 1468 10693 0.1373 0.1293
MCF 10A WYE-125132
10
uM
LJP6
 2
L07
 72
hr
 962 1363 10740 0.1269 0.1052
MCF 10A WYE-125132
10
uM
LJP6
 3
L07
 72
hr
 962 1451 10641 0.1364 0.1258
MCF 10A Barasertib
0.04
uM
LJP5
 1
D12
 72
hr
 962 1521 10714 0.1420 0.1408
MCF 10A Barasertib
0.04
uM
LJP5
 2
D12
 72
hr
 962 1347 10507 0.1282 0.1025
MCF 10A Barasertib
0.04
uM
LJP5
 3
D12
 72
hr
 962 1443 10315 0.1399 0.1257
MCF 10A Barasertib
0.12
uM
LJP5
 1
D11
 72
hr
 962 1376 10714 0.1284 0.1084
MCF 10A Barasertib
0.12
uM
LJP5
 2
D11
 72
hr
 962 1427 10507 0.1358 0.1211
MCF 10A Barasertib
0.12
uM
LJP5
 3
D11
 72
hr
 962 1485 10315 0.1440 0.1352
MCF 10A Barasertib
0.37
uM
LJP5
 1
D10
 72
hr
 962 1445 10714 0.1349 0.1241
MCF 10A Barasertib
0.37
uM
LJP5
 2
D10
 72
hr
 962 1244 10507 0.1184 0.0773
MCF 10A Barasertib
0.37
uM
LJP5
 3
D10
 72
hr
 962 1514 10315 0.1468 0.1416
MCF 10A Barasertib
1.11
uM
LJP5
 1
D09
 72
hr
 962 1447 10714 0.1351 0.1245